Results 71 to 80 of about 5,472 (201)

Prospective assessment of risk biomarkers of sinusoidal obstruction syndrome after hematopoietic cell transplantation

JCI Insight, 2023
BACKGROUND Currently, no laboratory tests exist to stratify for the risk of developing sinusoidal obstruction syndrome (SOS), an early endothelial complication after hematopoietic cell transplantation (HCT).
Yan Han, Alan Bidgoli, Brittany P. DePriest, Alejandra Méndez, Khadijeh Bijangi-Vishehsaraei, Evelio D. Perez-Albuerne, Robert A. Krance, Jamie Renbarger, Jodi L. Skiles, Sung W. Choi, Hao Liu, Sophie Paczesny   +11 more
doaj   +1 more source

Molecular interaction between natural IgG and ficolin - Mechanistic insights on adaptive-innate immune crosstalk [PDF]

, 2014
10.1038/srep03675Scientific ...
Anand, Ganesh Srinivasan, Ding, Jeakling, Panda, Saswati, Yang, Lifeng, Zhang, Jing   +4 more
core   +1 more source

Circulating ficolin-2 and ficolin-3 in normal pregnancy and pre-eclampsia

Clinical and Experimental Immunology, 2012
Summary Ficolins are soluble molecules of the innate immune system that recognize carbohydrate molecules on microbial pathogens, apoptotic and necrotic cells. They act through two distinct routes: initiating the lectin pathway of complement activation and mediating a primitive opsonophagocytosis.
Halmos, Amrita, Rigó, János Jr., Szijártó, János, Füst, György, Prohászka, Zoltán, Molvarec, Attila   +5 more
openaire   +4 more sources

Advancing IBD Management: A Literature Review on the Role of Non‐Invasive Blood‐Based Biomarkers in Predicting and Assessing Pharmacodynamic Response to Treatment

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Reliable biomarkers that enable noninvasive, longitudinal assessment of disease activity and therapeutic response remain a major unmet need in inflammatory bowel disease (IBD). While colonic biopsies are the gold standard for evaluating mucosal inflammation, their invasive nature and limited spatial and temporal resolution constrain their ...
Mohamed Hassanein, Li Xi, Rathi D. Ryan, Zhan (Harold) Ye, Nessy Tania, Yamato Sano, Joshua Varghese, Diogo Branquinho, Anna Sapone   +8 more
wiley   +1 more source

JNK1 activation predicts the prognostic outcome of the human hepatocellular carcinoma [PDF]

, 2009
BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide with an extremely poor prognosis. The classification of HCC based on the molecular signature is not well-established.
Fei Chen, Jianguo Chen, Kevin J Beezhold, Qingshan Chang, Vince Castranova, Xianglin Shi   +5 more
core   +3 more sources

Innate Immunity and Microbial Recognition in Reproduction: From Barrier Defense to Maternal–Fetal Tolerance

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Graphical abstract illustrating the barrier defense–tolerance framework of reproductive innate immunity. Across the female and male reproductive tracts and the maternal–fetal interface, epithelial barriers, innate sensors, immune cells, and microbial signals are integrated to preserve reproductive homeostasis.
Xianlin Rao, Li Zou, Yao Yao, Changling Liu   +3 more
wiley   +1 more source

Inherited deficiency of the initiator molecules of the lectin-complement pathway [PDF]

, 2010
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn Skoða/Opna(view/open)The complement system is an important immune system. Its activation results in membranolytic elimination of microbes and opsonization.
Björn Rúnar Lúðvíksson, Helga Bjarnadóttir   +1 more
core  

Two independent proteomic approaches provide a comprehensive analysis of the synovial fluid proteome response to Autologous Chondrocyte Implantation [PDF]

, 2018
Background: Autologous chondrocyte implantation (ACI) has a failure rate of approximately 20%, but it is yet to be fully understood why. Biomarkers are needed that can pre-operatively predict in which patients it is likely to fail, so that alternative or
AL Barabási, AM Bhosale, Catherine H. Botting, CH Hulme, Charlotte H. Hulme, CM Stoscheck, D Croft, D Saris, DH Sohn, DR Clemmons, E Chiaradia, E Ehrich, E Gruys, E Guney, E Roos, Emma L. Wilson, G Murphy, GJVM van Osch, H Fuller, Heidi R. Fuller, HJ Smith, HR Fuller, I Vastrik, J Lysholm, J Mateos, James B. Richardson, JB Richardson, Karina T. Wright, KS Lilley, KT Wright, KT Wright, L Balakrishnan, L Balakrishnan, M Bantscheff, M Bhattacharjee, M Vidal, Mandy J. Peffers, MF Hsueh, MJ Cowley, MM Herr, MN Dugard, Pete Gallacher, Q Wang, R Albert, R Noh, S Roberts, Sally L. Shirran, Sally Roberts, SD Gillogly, SY Ritter, T Bennike, T Nepusz, VB Kraus, VB Kraus, W Liao, W Liao, WH Busby, WW Wu, X Pan   +58 more
core   +5 more sources

Complement lectin pathway protein levels reflect disease activity in juvenile idiopathic arthritis: a longitudinal study of the Nordic JIA cohort

Pediatric Rheumatology Online Journal, 2019
Background To determine the serum levels of the lectin pathway proteins early in the disease course and 17 years after disease onset and to correlate the protein levels to markers of disease activity in participants from a population-based Nordic ...
Mia Glerup, Steffen Thiel, Veronika Rypdal, Ellen Dalen Arnstad, Maria Ekelund, Suvi Peltoniemi, Kristiina Aalto, Marite Rygg, Susan Nielsen, Anders Fasth, Lillemor Berntson, Ellen Nordal, Troels Herlin, for the Nordic Study Group of Pediatric Rheumatology (NoSPeR)   +13 more
doaj   +1 more source

Glycobiology of cell death: when glycans and lectins govern cell fate [PDF]

, 2013
Although one typically thinks of carbohydrates as associated with cell growth and viability, glycosylation also has an integral role in many processes leading to cell death.
A Büssing, A Shiratsuchi, A Sturm, AF Carlin, AF Swindall, B Brandt, BE Britigan, BN Stillman, C Lazar, C Villeneuve, C Zhu, CA Gabel, CF Brewer, D Paclik, E Cao, E Charlier, E Duvall, E Rapoport, EM Rapoport, F Bernerd, F Dall’Olio, F Gu, F Yu, FA Barr, FT Liu, G A Rabinovich, G Ion, G Majai, G Yogalingam, GA Rabinovich, GA Rabinovich, GA Rabinovich, GA Rabinovich, GA Rabinovich, GA Rabinovich, GC Fernández, GD Griffiths, GR Vasta, H Ise, H Sano, H Sano, HM Meesmann, HP Hahn, I Bournazou, I Kuwabara, JA Fulcher, JD Hernandez, JD Marth, JF Kerr, JH Lin, JT Nguyen, K Kollmann, K Lauber, K Moriwaki, K Moriwaki, K Suzuki, KE Pace, KW Wagner, L Eshkar Sebban, LA Earl, LC Paessens, LH Lu, LL Fu, M Cohen, M Dias-Baruffi, M Molinari, M Pang, M Rangachari, MA Toscano, MC Maiuri, ME Peter, ML Litvack, MM Fuster, MM Weck, MU Hutchins, N Maugeri, N Mazurek, N Mazurek, N Mazurek, N Oka, N Sharon, NB Caberoy, OM Shatnyeva, OT Keppler, P Desharnais, P Matarrese, P Schneider, P Smits, R G Lichtenstein, R Hanayama, R Hanayama, RA Lockshin, RG Morris, RS Maag, RY Yang, S Arur, S Eda, S Gupta, S Li, S Mukherjee, S Toda, S Wesselborg, SC Starossom, SJ Van Dyken, SJ Van Vliet, SR Stowell, SR Stowell, T Fukumori, T Fukumori, TL Schagat, TL Thurston, V Wells, VA Fadok, VM Abrahams, X Li, Y Kashio, Y Oda, Y Wang, Y Watanabe, Y Watanabe, Y Zhuo, YJ Lee, Z Liu, ZN Oltvai   +123 more
core   +2 more sources