Results 51 to 60 of about 5,472 (201)

Primary Ficolin-3 deficiency – Is it associated with increased susceptibility to infections?

Immunobiology, 2015
Ficolin-3 (also called H-ficolin or Hakata antigen) is the most potent activator of the lectin pathway of complement in vitro. Its genetically determined deficiency in Caucasians is associated with a frame-shift mutation +1637delC (rs28357092) of the FCN3 gene.
Mateusz, Michalski, Anna St, Świerzko, Izabela, Pągowska-Klimek, Zofia I, Niemir, Karolina, Mazerant, Iwona, Domżalska-Popadiuk, Maciej, Moll, Maciej, Cedzyński   +7 more
openaire   +2 more sources

Screening for immune-potentiating antigens from hepatocellular carcinoma patients after radiofrequency ablation by serum proteomic analysis

BMC Cancer, 2018
Background Radiofrequency ablation (RFA) can not only effectively kill hepatocellular carcinoma (HCC) tumour cells but also release tumour antigens that can provoke an immune response.
Shunli Shen, Hong Peng, Ye Wang, Ming Xu, Manxia Lin, Xiaoyan Xie, Baogang Peng, Ming Kuang   +7 more
doaj   +1 more source

Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]

, 2020
Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima, Al-Herz, Waleed, Bousfiha, Aziz, Casanova, Jean-Laurent, Chatila, Talal, Cunningham-Rundles, Charlotte, Etzioni, Amos, Franco, Jose Luis, Holland, Steven M, Jeddane, Leila, Klein, Christoph, Morio, Tomohiro, Ochs, Hans D, Oksenhendler, Eric, Picard, Capucine, Puck, Jennifer, Sullivan, Kathleen E, Tangye, Stuart G, Torgerson, Troy R   +18 more
core  

Ficolin-3 activity towards the opportunistic pathogen, Hafnia alvei

Immunobiology, 2015
Ficolin-3 (also called H-ficolin or Hakata antigen) is a complement-activating pattern recognition molecule, possessing a fibrinogen-like domain involved in carbohydrate binding. Amongst human ficolins, Ficolin-3 has the highest concentration in serum and is the most potent lectin pathway activator in vitro.
Mateusz, Michalski, Anna, St Swierzko, Jolanta, Lukasiewicz, Aleksandra, Man-Kupisinska, Iwona, Karwaciak, Patrycja, Przygodzka, Maciej, Cedzynski   +6 more
openaire   +2 more sources

Proteomic analysis of human plasma in chronic rheumatic mitral stenosis reveals proteins involved in the complement and coagulation cascade [PDF]

, 2014
BACKGROUND: Rheumatic fever in childhood is the most common cause of Mitral Stenosis in developing countries. The disease is characterized by damaged and deformed mitral valves predisposing them to scarring and narrowing (stenosis) that results in left ...
Arun Bandyopadhyay, Mahesh J Kulkarni, Mashanipalya G Jagadeeshaprasad, Monodeep Biswas, Sanjib Pattari, Santanu Dutta, Somaditya Mukherjee, Sudip K Ghosh, Tanima Banerjee   +8 more
core   +1 more source

The Influence of the Lectin Pathway of Complement Activation on Infections of the Respiratory System

Frontiers in Immunology, 2020
Lung diseases are among the leading causes of morbidity and mortality. Complement activation may prevent a variety of respiratory infections, but on the other hand, could exacerbate tissue damage or contribute to adverse side effects. In this review, the
Anna S. Świerzko, Maciej Cedzyński
doaj   +1 more source

Polymorphisms of the FCN2 Gene 3’UTR Region and Their Clinical Associations in Preterm Newborns

Frontiers in Immunology, 2021
Ficolin-2 is regarded as an important innate immunity factor endowed with both lectin (carbohydrate recognition) qualities and ability to induce complement activation.
Anna S. Świerzko, Dariusz Jarych, Gabriela Gajek, Karolina Chojnacka, Paulina Kobiela, Maja Kufelnicka-Babout, Mateusz Michalski, Katarzyna Sobczuk, Agnieszka Szala-Poździej, Misao Matsushita, Jan Mazela, Iwona Domżalska-Popadiuk, David C. Kilpatrick, Jarosław Kalinka, Hideharu Sekine, Maciej Cedzyński   +15 more
doaj   +1 more source

Autologous chondrocyte implantation-derived synovial fluids display distinct responder and non-responder proteomic profiles [PDF]

, 2017
Hulme, Charlotte H. & Wilson, Emma L. - Equal contributorsBackground Autologous chondrocyte implantation (ACI) can be used in the treatment of focal cartilage injuries to prevent the onset of osteoarthritis (OA).
AI Vasara, B Hopwood, BT Sherman, Charlotte H. Hulme, CM Stoscheck, CT Thorpe, D Saris, D Seny de, DA Wolff, Deborah M. Simpson, DL Cecil, DS Gibson, E Ehrich, E Roos, Emma L. Wilson, F Ceuninck De, FE Watt, G Knutsen, G Murphy, H Smith, H Zreiqat, I Tchetverikov, J Lysholm, J Mateos, J Shen, J Wanner, JA Vizcaino, James B. Richardson, JB Richardson, K Nganvongpanit, Karina T. Wright, KT Wright, LA Collins-Racie, Mandy J. Peffers, MF Hsueh, MF Pietschmann, MJ Peffers, MJ Peffers, MK Lotz, MN Dugard, N Balmain, P Germain, P Niemeyer, P Niemeyer, P Niemeyer, Pete Gallacher, PK Jaiswal, PM Jungmann, R Serra, RR Yammani, S Hartwig, S Roberts, Sally Roberts, SD Gillogly, SM Wasilko, SY Ritter, V Kraus, VB Kraus, W Liao, W Liao, X Yang, Y Su, Y Yoshihara   +62 more
core   +1 more source

Proteomic Analysis of Humoral Immune Components in Bronchoalveolar Lavage of Patients Infected or Colonized by Aspergillus fumigatus

Frontiers in Immunology, 2021
Humoral immune components have been individually studied in the context of interaction of host with Aspergillus fumigatus, a major airborne fungal pathogen. However, a global view of the multitude and complex nature of humoral immune components is needed
Sarah Dellière, Sarah Dellière, Sarah Dellière, Magalie Duchateau, Sarah Sze Wah Wong, Quentin Giai Gianetto, Quentin Giai Gianetto, Hélène Guegan, Mariette Matondo, Jean-Pierre Gangneux, Vishukumar Aimanianda   +10 more
doaj   +1 more source

MBL-associated serine protease-3 circulates in high serum concentrations predominantly in complex with Ficolin-3 and regulates Ficolin-3 mediated complement activation

Immunobiology, 2010
The human lectin complement pathway (LCP) involves circulating complexes consisting of mannose-binding lectin (MBL) or ficolins in association with serine proteases named MASP-1, -2 and -3 and a non-enzymatic protein, sMAP. MASP-3 originates from the MASP1 gene through differential splicing and little is known about its biological characteristics.
Skjoedt, Mikkel-ole, Palarasah, Yaseelan, Munthe-fog, Lea, Jie Ma, Ying, Weiss, Gudrun, Skjodt, Karsten, Koch, Claus, Garred, Peter   +7 more
openaire   +4 more sources