Results 41 to 50 of about 5,472 (201)

Association of low ficolin-2 concentration in cord serum with respiratory distress syndrome in preterm newborns

Frontiers in Immunology, 2023
IntroductionFicolin-2 is a serum pattern recognition molecule, involved in complement activation via the lectin pathway. This study aimed to investigate the association of ficolin-2 concentration in cord blood serum with complications related to ...
Gabriela Gajek, Anna S. Świerzko, Dariusz Jarych, Damian Mikulski, Paulina Kobiela, Karolina Chojnacka, Maja Kufelnicka-Babout, Agnieszka Szala-Poździej, Jędrzej Chrzanowski, Katarzyna Sobczuk, Wojciech Fendler, Misao Matsushita, Iwona Domżalska-Popadiuk, Jan Mazela, Jarosław Kalinka, Hideharu Sekine, Maciej Cedzyński   +16 more
doaj   +1 more source

Deciphering the ovarian cancer ascites fluid peptidome [PDF]

, 2014
BACKGROUND: Conventional proteomic approaches have thus far been unable to identify novel serum biomarkers for ovarian cancer that are more sensitive and specific than the current clinically used marker, CA-125.
Anand Bery, Christopher R Smith, Eleftherios P Diamandis, Felix Leung, Vathany Kulasingam   +4 more
core   +2 more sources

Complement activation and its prognostic role in post-cardiac arrest patients [PDF]

, 2014
Cardiac arrest causes generalized ischemia/hypoxia, and subsequent resuscitation inflicts reperfusion injury, the pathology of which is not fully understood.
Bisschops, Bottiger, Cervera, Dunkelberger, Fust, Gombos, Gorsuch, Kohler, Lindsberg, Matsushita, Mocco, Oddo, Pedersen, Prohaszka, Shinozaki, Szeplaki, Turner, Wojtczak-Soska   +17 more
core   +1 more source

Molecular serum signature of treatment resistant depression [PDF]

, 2016
Rationale: A substantial number of patients suffering from major depressive disorder (MDD) do not respond to multiple trials of anti-depressants, develop a chronic course of disease and become treatment resistant.
Arolt, V, Bahn, S, Chan, MK, Cooper, JD, Grosse, L, Rothermundt, M, Ruland, T, Stocki, P   +7 more
core   +1 more source

Dectin-2 recognises mannosylated O-antigens of human opportunistic pathogens and augments lipopolysaccharide activation of myeloid cells [PDF]

, 2016
Lipopolysaccharide (LPS) consists of a relatively conserved region of lipid A and core-oligosaccharide, and a highly variable region of O-antigen polysaccharide.
Akatsuka, Alexandra Wittmann, Aucken, Avril, Bergman, Blasius, Cardile, Carpenter, Carter, Chris Whitfield, Dillon, Dimitra Lamprinaki, Dodgson, Drickamer, Eder, Ewa Katzenellenbogen, Feinberg, Ferwerda, Gantner, García-Vallejo, Gavino, Gordeuk, Gringhuis, Herget, Inagaki, Ishikawa, Ito, Jansson, Jiang, Kanazawa, Katzenellenbogen, Kawai, Kawasaki, Kawasaki, Kazuo Yamamoto, Khanna, Kocharova, Kristian M. Bowles, Kubler-Kielb, Lai, Lin, Liu, Liu, Lugowski, Lukasiewicz, Lutz, Macauley, Mann, McGreal, Mesci, Michalski, Miller, Nagaoka, Nagarjuna, Naoki Matsumoto, Norihito Kawasaki, Norimoto, Olsthoorn, Papadopoulos, Parsons, Pfrengle, Podschun, Prehm, Rick, Robinson, Rudick, Saijo, Sanderson, Sato, Shinobu Saijo, Swierzko, Takashi Nishimura, Taylor, Tichaczek-Goska, Tsolis, van Kooyk, Vinogradov, Yoichiro Iwakura, Yonekawa, Yu, Yuriy A. Knirel, Zamze, Zhao   +82 more
core   +1 more source

Local and Systemic Concentrations of Pattern Recognition Receptors of the Lectin Pathway of Complement in a Cohort of Patients With Interstitial Lung Diseases

Frontiers in Immunology, 2020
BackgroundThe role of the lectin pathway of complement in the pathogenesis of interstitial lung diseases (ILDs) is largely unknown. Pattern recognition receptors (PRR) of the lectin pathway are involved in the clearance of apoptotic cells either via ...
Severin Vogt, Severin Vogt, Marten Trendelenburg, Marten Trendelenburg, Marten Trendelenburg, Michael Tamm, Michael Tamm, Daiana Stolz, Daiana Stolz, Katrin Esther Hostettler, Katrin Esther Hostettler, Michael Osthoff, Michael Osthoff, Michael Osthoff   +13 more
doaj   +1 more source

Collectins and ficolins in neonatal health and disease

Frontiers in Immunology, 2023
The immune system starts to develop early in embryogenesis. However, at birth it is still immature and associated with high susceptibility to infection.
Maciej Cedzyński, Anna S. Świerzko
doaj   +1 more source

H-ficolin binds Aspergillus fumigatus leading to activation of the lectin complement pathway and modulation of lung epithelial immune responses. [PDF]

, 2015
Aspergillus fumigatus is an opportunistic fungal pathogen that typically infects the lungs of immunocompromised patients leading to a high mortality.
Akaiwa, Ali, Azuma, Balloy, Bidula, Bidula, Bidula, D'Haese, De Pauw, DeHart, Foster, Garlatti, Hammond, Hearn, Hummelshøj, Kenawy, Latge, Le, Luo, Ma, Ma, Ma, Madan, Mambula, Martin, Martinez, Matsushita, Matsushita, Matsushita, Meier, Munthe-Fog, Neth, Romani, Rubino, Schelenz, Schelenz, Steele, Steinbach, Sturtevant, Taccone, Thornton, Torok, Werner, Wetering, Zacho, Zhang, Zhao   +46 more
core   +1 more source

Associations of Ficolins With Hematological Malignancies in Patients Receiving High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantations

Frontiers in Immunology, 2020
A prospective study of 312 patients [194 with multiple myeloma (MM) and 118 with lymphomas (LYMPH)] receiving high-dose chemotherapy and autologous hematopoietic stem cell transplantation (auto-HSCT) was conducted.
Anna S. Świerzko, Mateusz Michalski, Anna Sokołowska, Mateusz Nowicki, Agnieszka Szala-Poździej, Łukasz Eppa, Iwona Mitrus, Anna Szmigielska-Kapłon, Małgorzata Sobczyk-Kruszelnicka, Katarzyna Michalak, Aleksandra Gołos, Agnieszka Wierzbowska, Sebastian Giebel, Krzysztof Jamroziak, Marek L. Kowalski, Olga Brzezińska, Olga Brzezińska, Steffen Thiel, Misao Matsushita, Jens C. Jensenius, Gabriela Gajek, Maciej Cedzyński   +21 more
doaj   +1 more source

Distinct Roles of Classical and Lectin Pathways of Complement in Preeclamptic Placentae

Frontiers in Immunology, 2022
Pre-eclampsia is a pregnancy complication characterized by defective vascular remodeling in maternal decidua responsible for reduced blood flow leading to functional and structural alterations in the placenta. We have investigated the contribution of the
Beatrice Belmonte, Beatrice Belmonte, Alessandro Mangogna, Alessandro Gulino, Valeria Cancila, Gaia Morello, Chiara Agostinis, Roberta Bulla, Giuseppe Ricci, Giuseppe Ricci, Filippo Fraggetta, Marina Botto, Marina Botto, Peter Garred, Peter Garred, Francesco Tedesco   +15 more
doaj   +1 more source