Results 51 to 60 of about 123,835 (272)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Extracellular vesicle and particle isolation from human and murine cell lines, tissues, and bodily fluids

STAR Protocols, 2021
Summary: We developed a modified protocol, based on differential ultracentrifugation (dUC), to isolate extracellular vesicles and particles (specifically exomeres) (EVPs) from various human and murine sources, including cell lines, surgically resected ...
Linda Bojmar, Han Sang Kim, Gabriel C. Tobias, Fanny A. Pelissier Vatter, Serena Lucotti, Kofi Ennu Gyan, Candia M. Kenific, Zurong Wan, Kyung-A Kim, DooA Kim, Jonathan Hernandez, Virginia Pascual, Todd E. Heaton, Michael P. La Quaglia, David Kelsen, Tanya M. Trippett, David R. Jones, William R. Jarnagin, Irina R. Matei, Haiying Zhang, Ayuko Hoshino, David Lyden   +21 more
doaj   +1 more source

Comment on "Pinched Flow Fractionation: Continuous Size Separation of Particles Utilizing a Laminar Flow Profile in a Pinched Microchannel"

, 2007
[First paragraph] In a recent paper Yamada et al. propose the novel concept of "pinched flow fractionation" (PFF) for the continuous size separation and analysis of particles in microfabricated lab-on-a-chip devices.
Mortensen, Niels Asger
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Preparation of tailor-made supported catalysts using asymmetric flow field flow fractionation and their application in hydrogenation

Nanotechnology Reviews, 2014
The optical, chemical, and catalytic properties of metallic nanoparticles (NPs) depend strongly on their particle size and shape. Therefore, the preparation of monodisperse metallic NPs is very important for fundamental studies and practical applications.
Baumgard Jens, Pohl Marga-Martina, Kragl Udo, Steinfeldt Norbert   +3 more
doaj   +1 more source

Accelerated Particle Separation in a DLD Device at Re > 1 Investigated by Means of µPIV

Micromachines, 2019
A pressure resistant and optically accessible deterministic lateral displacement (DLD) device was designed and microfabricated from silicon and glass for high-throughput fractionation of particles between 3.0 and 7.0 µm comprising array segments of ...
Jonathan Kottmeier, Maike Wullenweber, Sebastian Blahout, Jeanette Hussong, Ingo Kampen, Arno Kwade, Andreas Dietzel   +6 more
doaj   +1 more source

Partition-Induced Vector Chromatography in Microfluidic Devices

, 2010
The transport of Brownian particles in a slit geometry in the presence of an arbitrary two-dimensional periodic energy landscape and driven by an external force or convected by a flow field is investigated by means of macrotransport theory.
Bahukudumbi, Balvin, Bhagat, Brenner, Brenner, Burada, Carlo, Choi, Choi, Choi, Davis, Dorfman, Dorfman, Eijkel, Ermak, Evander, Frechette, Gascoyne, German Drazer, Giddings, Giddings, Giddings, Giddings, Han, Han, Happel, Herrmann, Huang, Hughes, Jacobs, Jonáš, Jorge A. Bernate, Kovarik, Kowalkowski, Kralj, Kulrattanarak, Laachi, Li, Mao, Morton, Morton, Pamme, Pamme, Park, Pawar, Risken, Sai, Staben, Takagi, Vastamäki, Wang, Wu, Yamada, Yamada, Zwanzig   +54 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Influence of Soil Colloids on the Transport of Cd²⁺ and Pb²⁺ under Different pH and Ionic Strength Conditions

Agronomy
The co-transport of contaminants by soil colloids can generate substantial environmental risk, and this behavior is greatly affected by environmental conditions.
Zihao Ye, Dihao Xu, Jiawen Zhong, Shuang Gao, Jinjin Wang, Yulong Zhang, Huijuan Xu, Yongtao Li, Wenyan Li   +8 more
doaj   +1 more source

Fermentation pH Modulates the Size Distributions and Functional Properties of Gluconobacter albidus TMW 2.1191 Levan

Frontiers in Microbiology, 2017
Bacterial levan has gained an increasing interest over the last decades due to its unique characteristics and multiple possible applications. Levan and other exopolysaccharides (EPSs) production are usually optimized to obtain the highest concentration ...
Tharalinee Ua-Arak, Frank Jakob, Rudi F. Vogel   +2 more
doaj   +1 more source