Results 91 to 100 of about 14,521,432 (345)
, 2016 This study explores the feasibility of identifying the effective soil hydraulic parameterization of a layered soil profile by using a conventional unsteady drainage experiment leading to field capacity. The flux‐based field capacity criterion is attained
P. Nasta, N. Romano
semanticscholar +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Division of Global Public Health Capacity Development 2008 annual report [PDF]
Based in Atlanta, Georgia (U.S.A.), the Division of Global Public Health Capacity Development (DGPHCD) is part of the Coordinating Office for Global Health at the U .S . Centers for Disease Control and Prevention.
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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
The Theory Question in Research Capacity Building in Education: Towards an Agenda for Research and Practice [PDF]
, 2011 The question of capacity building in education has predominantly been approached with regard to the methods and methodologies of educational research. Far less attention has been given to capacity building in relation to theory.
Edwards, R. G. +11 more
core +1 more source
Unjuk Kerja Mesin Pemanen Padi (Oryza sativa) Kombinasi Mini (Mini Combine Harvester)
Jurnal Teknik Pertanian Lampung, 2021 Mini combine harvester is a modern machine used for cutting rice, threshing and cleaning grain while walking in the field. This machine helps farmers where, time and energy to harvest more efficiently and does not require a large amount of labor like ...
Mochamad Zakky +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Missouri Work Zone Capacity: Results of Field Data Analysis, TPF-5(081), 2011
, 2011 This report presents the results of work zone field data analyzed on interstate highways in Missouri to determine the mean breakdown and queue-discharge flow rates as measures of capacity.
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