Results 81 to 90 of about 1,004,664 (267)
Determination of field capacity in the Chibunga and Guano rivers micro-basins. [PDF]
F1000Res, 2021 Mendoza B +8 more
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Soil Hydraulic Properties Estimated from Evaporation Experiment Monitored by Low-Cost Sensors
AgronomyThe estimation of soil hydraulic properties—such as water retention and hydraulic conductivity—is essential for irrigation management and agro-hydrological modeling.
Tallys Henrique Bonfim-Silva +5 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Assessing the soil physical and chemical properties of long-term pomelo orchard based on tree growth
Open AgricultureThe investigation in three groups of pomelo trees (good, average, bad) was conducted. Each group included 15 orchards. The number of soil samples collected for analysis is 15 samples × 2 depths (0–15 cm and 15–30 cm) × 3 groups of plants = 90 soil ...
Linh Tran Ba +4 more
doaj +1 more source
Remote Sensing, 2019 The soil minerals determine essential soil properties such as the cation exchange capacity, texture, structure, and their capacity to form bonds with organic matter.
Irena Ymeti +2 more
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Ciência e Agrotecnologia, 2013 Water retention in soil is used in many agronomic and environmental applications, but its direct measurement is time-consuming and expensive. Therefore, pedotransfer functions (PTFs) are alternatives to obtain this information faster and more ...
Walbert Júnior Reis dos Santos +4 more
doaj