Results 121 to 130 of about 10,818,476 (313)
Cybersecurity Capacity Review – Federative Republic of Brazil
, 2020 Excerpt from the executive summary - The Global Cyber Security Capacity Centre (GCSCC or ‘the Centre’) undertook a review of the maturity of cybersecurity capacity in Brazil at the invitation of, and in collaboration with, the Secretariat of the Inter ...
Global Cyber Security Capacity Centre
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Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Playing With Reality: Emergency Capacity Building Project simulations case study
, 2012 This Emergency Capacity Building (ECB) Project simulation case study focuses on the lessons learnt from implementing the ECB Project multi-agency simulations at the national level between April 2010 and March 2012, using the ECB Simulations ...
Lumsdon, Sarah, Hockaday, David
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
AgronomyNutrient seed priming is a promising technique for enhancing nutrient uptake and improving crop growth, especially under water stress conditions. This study investigated the effects of various priming treatments on water stress tolerance and the uptake ...
Mufunwa Maphalaphathwa +1 more
doaj +1 more source
Penentuan nilai field capacity pada sampah segar Dan sampah lama
, 2012 In determining leachate generation, the value of field capacity waste is one of the parameters that determine the amount of leachate which is formed against, because the field capacity (FC) is amount of water that may be stored by the waste until it has ...
Samin .
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source