Results 111 to 120 of about 810,966 (282)

Central Dysmyelination in SSADH‐Deficient Humans and Mice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer, Henry H. C. Lee, Edward Yang, Cesar Alves, Mariarita Bertoldi, Caitlyn Fung, Spencer V. Steele, Eren Kule, Zijie Jin, Alexander Rotenberg, Jean‐Baptiste Roullet, Phillip L. Pearl   +11 more
wiley   +1 more source

Super Yang-Mills theory in 10+2 dimensions, The 2T-physics Source for N=4 SYM and M(atrix) Theory

, 2010
In this paper we construct super Yang-Mills theory in 10+2 dimensions, a number of dimensions that was not reached before in a unitary supersymmetric field theory, and show that this is the 2T-physics source of some cherished lower dimensional field ...
Bars, Itzhak, Kuo, Yueh-Cheng
core  

Longitudinal Study of Salivary Biomarkers in the Definition of Clinico‐Molecular Progression of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
Longitudinal changes in salivary biomarkers in Parkinson’s disease (PD) from early (T0) to 4‐year follow‐up (T1), quantified by ELISA: oligomeric and total α‐synuclein, total and phosphorylated tau, MAP1LC3B (autophagy), and TNFa (inflammation). Blue arrows indicate direction of change at T1 vs T0 (up = increase; down = decrease).
Maria Ilenia De Bartolo, Daniele Belvisi, Matteo Costanzo, Claudia Caturano, Francesco Emanuele Bellomi, Carolina Cutrona, Flavia Aiello, Giorgio Leodori, Massimo Marano, Romina Mancinelli, Antonella Conte, Giovanni Fabbrini, Alfredo Berardelli, Giorgio Vivacqua   +13 more
wiley   +1 more source

On fast quenches and spinning correlators

Journal of High Energy Physics, 2018
We study global quantum quenches in a continuous field theoretic system with UV fixed point. Assuming that the characteristic inverse time scale of the smooth quench is much larger than all scales inherent to the system except for the UV-cutoff, we ...
Mikhail Goykhman, Tom Shachar, Michael Smolkin   +2 more
doaj   +1 more source

Purkinje Cell Loss in Essential Tremor: Collective Data From 215 Brains Over a 21‐Year Period

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Essential tremor is a highly prevalent movement disorder. Pathological changes observed in essential tremor cerebella center around Purkinje cells and neighboring neuronal populations. Postmortem studies have variably, but not always, shown reduced Purkinje cell counts in essential tremor compared to controls.
Chloë A. Kerridge, Roberto S. Hernandez, Nora C. Hernandez, Phyllis L. Faust, Elan D. Louis   +4 more
wiley   +1 more source

Mellin bootstrap for scalars in generic dimension

Journal of High Energy Physics, 2018
We use the recently developed framework of the Mellin bootstrap to study perturbatively free scalar CFTs in arbitrary dimensions. This approach uses the crossing-symmetric Mellin space formulation of correlation functions to generate algebraic bootstrap ...
John Golden, Daniel R. Mayerson
doaj   +1 more source

Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and CSF Cell Composition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich, Tilman Schneider‐Hohendorf, Eric Baetscher, Evan L. Riddle, Marie Deffner, Emily Katsnelson, Janine Ferrant‐Orgettas, Julie Czerkowicz, John Anderson, Susan E. Goelz, Nicholas Schwab   +10 more
wiley   +1 more source

Deformations of Fermionic Quantum Field Theories and Integrable Models

, 2012
Considering the model of a scalar massive Fermion, it is shown that by means of deformation techniques it is possible to obtain all integrable quantum field theoretic models on two-dimensional Minkowski space which have factorizing S-matrices ...
A.B. Zamolodchikov, B. Schroer, C. Dappiaggi, D. Buchholz, D. Buchholz, D. Buchholz, D. Buchholz, D. Buchholz, D. Iagolnitzer, E. Abdalla, F.A. Smirnov, G. Lechner, G. Lechner, G. Lechner, H. Grosse, H. Grosse, M. Reed, O. Bratteli, R. Jost, R.F. Streater, Sabina Alazzawi, W. Rudin   +21 more
core   +1 more source

Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug‐Resistant Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To develop a novel deep‐learning model of clinical DWI tractography that can accurately predict the general assessment of epilepsy severity (GASE) in pediatric drug‐resistant epilepsy (DRE) and test if it can screen diverse neurocognitive impairments identified through neuropsychological assessments.
Jeong‐Won Jeong, Min‐Hee Lee, Hiroshi Uda, Yoon Ho Hwang, Michael Behen, Aimee Luat, Csaba Juhász, Eishi Asano   +7 more
wiley   +1 more source

Resummation at finite conformal spin

Journal of High Energy Physics, 2019
We generalize the computation of anomalous dimension and correction to OPE coefficients at finite conformal spin considered recently in [1, 2] to arbitrary space-time dimensions.
Carlos Cardona, Sunny Guha, Surya Kiran Kanumilli, Kallol Sen   +3 more
doaj   +1 more source