Results 61 to 70 of about 46,456 (217)

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

All class S $$ \mathcal{S} $$ theories of type-A originate from orbi-instantons

Journal of High Energy Physics
A surprising relation between 4d N $$ \mathcal{N} $$ = 2 class S $$ \mathcal{S} $$ superconformal field theories of Type-A and 6d N $$ \mathcal{N} $$ = (1, 0) orbi-instanton theories is investigated.
Simone Giacomelli, William Harding, Noppadol Mekareeya, Alessandro Mininno   +3 more
doaj   +1 more source

Thermal CFTs in momentum space

Journal of High Energy Physics, 2020
We study some aspects of conformal field theories at finite temperature in momentum space. We provide a formula for the Fourier transform of a thermal conformal block and study its analytic properties.
Andrea Manenti
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Analytic Euclidean bootstrap

Journal of High Energy Physics, 2019
We solve crossing equations analytically in the deep Euclidean regime. Large scaling dimension ∆ tails of the weighted spectral density of primary operators of given spin in one channel are matched to the Euclidean OPE data in the other channel ...
Baur Mukhametzhanov, Alexander Zhiboedov
doaj   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

On non-linear chiral 4-form theories in D = 10

Journal of High Energy Physics
We consider properties of non-linear theories of a chiral 4-form gauge field A 4 in ten space-time dimensions with an emphasis on a subclass of these theories which are invariant under the D = 10 conformal symmetry. We show that general results regarding
Jessica Hutomo, Kurt Lechner, Dmitri P. Sorokin   +2 more
doaj   +1 more source

Entanglement entropy in generalised quantum Lifshitz models

Journal of High Energy Physics, 2019
We compute universal finite corrections to entanglement entropy for generalised quantum Lifshitz models in arbitrary odd spacetime dimensions. These are generalised free field theories with Lifshitz scaling symmetry, where the dynamical critical exponent
J. Angel-Ramelli, V. Giangreco M. Puletti, L. Thorlacius   +2 more
doaj   +1 more source