Results 101 to 110 of about 12,963 (306)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Poverty and the transformation of the welfare (state) arrangement. Food banks and the charity economy in Germany

open access: yesSocial Work and Society, 2019
We are currently witnessing a shift in the public response to poverty within our societies. The establishment and consolidation of food banks in Germany and in many other western European countries change the character of the welfare state.
Holger Schoneville
doaj   +2 more sources

THE BRAZILIAN PRESIDENCY AT THE G20: THE NECESSARY INTERSECTORALITY BETWEEN THE FIGHT AGAINST HUNGER, THE BIOECONOMY AND CLIMATE CHANGE TO BUILD A JUST WORLD AND A SUSTAINABLE PLANET

open access: yesRevista Tempo do Mundo
Brazil's Presidency in the G20 in 2024 marks a turning point by proposing an integrated approach to address the interconnected challenges of combating hunger, climate change, and promoting bioeconomy.
Júlia Mascarello Fundação   +2 more
doaj   +1 more source

Five Decades of Consumption and Income Poverty [PDF]

open access: yes
This paper examines poverty in the United States from 1960 through 2005. We investigate how poverty rates and poverty gaps have changed over time, explore how these trends differ across family types, contrast these trends for several different income and
Bruce D. Meyer, James X. Sullivan
core  

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Infectious disease research in developing countries: positioning science to address poverty and stimulate human development

open access: yesJournal of Infection in Developing Countries, 2007
"Science must be directed towards fighting and overcoming poverty and disease and in raising the standard of life of the people of the earth; its aims must be for the promotion of peace and, through peace, the happiness of mankind.
Iruka N. Okeke
doaj  

A Profile of the North West Province: Demographics, Poverty, Inequality and Unemployment [PDF]

open access: yes
This paper forms part of a series of papers that present profiles of South Africa's provinces, with a specific focus on key demographic statistics, poverty and inequality estimates, and estimates of unemployment. In this volume comparative statistics are
Pauw, Kalie
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

A Profile of the Western Cape Province: Demographics, Poverty, Inequality and Unemployment [PDF]

open access: yes
This paper forms part of a series of papers that present profiles of South Africa's provinces, with a specific focus on key demographic statistics, poverty and inequality estimates, and estimates of unemployment. In this volume comparative statistics are
Pauw, Kalie
core   +1 more source

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