Results 61 to 70 of about 666,264 (255)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Textos & Contextos (Porto Alegre), 2011 This paper illuminates some of the gendered challenges raised by the new ways of thinking social protection in the region. To discuss this, it studies the Conditional Cash Transfers (CCTs) developed in Chile. Based on the example of the Puente programme -
Tabbush, Constanza
doaj
Poverty and Employment in Timber-Dependent Counties [PDF]
One of the most controversial aspects of federal and state policies aimed at protecting old-growth ecosystems has been the potential impact of job losses on local economies.
Fortmann, Louise +3 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Tackling poverty: tackling health inequalities
, 2009 The purpose of this paper is to explore the impact of poverty and health inequalities among communities of interest participating in the Combat Poverty Building Healthy Communities (BHC) programme 2005 to ...
Burke, Sara
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Book review : Fighting poverty
, 2002 Review of: Haroon Bhorat et al. (eds). Fighting poverty.
Roberts, Benjamin J. (Benjamin Joseph), 1946-
core +1 more source
Multi-dimensional poverty: a bibliometric analysis and content co-occurrence literature review
Humanities & Social Sciences CommunicationsThis research reviewed studies on multi-dimensional poverty based on a bibliometric analysis and content co-occurrence literature review. Using VOSviewer, a bibliometric analysis of 1513 journal publications extracted from the Scopus database was ...
Tamisai Chipunza, Lungile Ntsalaze
doaj +1 more source