Results 91 to 100 of about 21,508 (266)
Applied Sciences, 2021 The aim of this study was to investigate the effect of the Coptis chinensis, Glycyrrhiza uralensis, and fermented Glycine max (3Hb) extract on lipid barrier recovery and the alleviation of atopic dermatitis (AD). The 3Hb extract was administered to lipid
Beom-Chan Park +3 more
doaj +1 more source
Atopic Dermatitis Host and Environment Model: Revisiting Therapeutic Options [PDF]
, 2020 Atopic Dermatitis affects both children and adults and is a serious health concern in many countries. AD is a complex disease with host and environmental factors underlying its pathology. Its treatment is multidimensional reflecting the diverse nature of
Abreu, C +3 more
core +1 more source
GP37 Is Different From Filaggrin
Journal of Investigative Dermatology, 1990 The identity of two differentiation markers of human epidermis, filaggrin and a Concanavalin A (Con-A) reactive glycoprotein of 37 kD, has been studied. Human epidermis was extracted in Nonidet P-40 buffer, and the soluble proteins were separated by two-dimensional electrophoresis.
Reano, Alain +2 more
openaire +2 more sources
Sleep Research, EarlyView.Abstract Background Sleep deprivation leads to changes in circadian rhythm, causing skin problems and aging. Whether acute sleep deprivation can be normalized after 14 days of natural skin metabolism is an important indicator for guiding treatment of sleep‐related skin physiological changes and mechanisms.
Qianxin Zhu +7 more
wiley +1 more source
Role of Antimicrobial Peptides in the Pathogenesis of Atopic Dermatitis
The Journal of Dermatology, EarlyView.ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by barrier dysfunction, immune dysregulation, and microbial dysbiosis. Recent studies have highlighted the multifaceted roles of antimicrobial peptides (AMPs) both as innate defenders against microbial invasion and as regulators of immune responses and skin barrier ...
Ge Peng +9 more
wiley +1 more source
Acta Dermato-Venereologica, 2017 Epidermal filaggrin level is affected by ultraviolet B irradiation in animal and experimental models. This study examined the effect of ultraviolet B irradiation on epidermal filaggrin and natural moisturizing factors in vivo in healthy adults (n = 22 ...
Stine Simonsen +4 more
doaj +1 more source
, 2016 Atopic eczema is an itchy inflammatory skin disease with a chronic relapsing–remitting course; it has increased in prevalence in recent decades and now affects up to 25% of school-aged children in the developed world and up to 10% of adults.
Deckert +7 more
core +2 more sources
Journal of the Royal College of Physicians of Edinburgh, 2008 Recent genetic findings demonstrate an important role for the epidermal protein filaggrin in the aetiology of atopic diseases, including asthma as well as eczema. Filaggrin is critical to the conversion of keratinocytes to the protein/lipid squames that compose the stratum corneum, the outermost barrier layer of the skin.
null R Weller, null WHI McLean
openaire +1 more source
The Journal of Dermatology, EarlyView.ABSTRACT Atopic dermatitis (AD) involves chronic eczema resulting from barrier dysfunction. Fine bubble (FB) technology generates microbubbles (< 100 μm) and ultrafine bubbles (< 1 μm) for surfactant‐sparing cleansing. We assessed the short‐term safety of an FB shower in AD.
Hiroshi Kato +9 more
wiley +1 more source
Clinical presentation of atopic dermatitis by filaggrin gene mutation status during the first 7 years of life in a prospective cohort study. [PDF]
PLoS ONE, 2012 BackgroundFilaggrin null mutations result in impaired skin barrier functions, increase the risk of early onset atopic dermatitis and lead to a more severe and chronic disease.
Charlotte Giwercman Carson +4 more
doaj +1 more source