Results 91 to 100 of about 21,702 (299)

Filaggrin-null mutations are associated with increased maturation markers on Langerhans cells [PDF]

, 2016
Background Mutations in the gene encoding filaggrin (FLG), an epidermal structural protein, are the strongest risk factor identified for the development of atopic dermatitis (AD).
Andrew J. Muinonen-Martin, Angelova-Fischer, Banchereau, Bashir, Berth-Jones, Brown, Chu, Claire S. Leitch, Correale, Cunjing Yu, Dahl, Di Gennaro, Eenass Natafji, Elias, Gibbs, Gibbs, Gibbs, Gilmour, Gilmour, Harriott-Smith, Jürgen Schwarze, Kammeyer, Kammeyer, Kaneko, Kezic, Laihia, Leung, Linda E. Campbell, Loffler, McAleer, McGrath, Meunier, Nayani Madarasingha, Norval, Pasanen, Pasanen, Paul M. Fitch, Peltonen, Pinnagoda, Prechtel, Richard B. Weller, Roland Chu, Romani, Romani, Ross, Sadhu, Sarah E.M. Howie, Seneschal, Sergeant, Sharizan Abdul-Ghaffar, Shibaki, Smith, W.H. Irwin McLean, Williams, Yoshida, Zoë C. Venables   +55 more
core   +4 more sources

Microfluidic Synthesis of Collagen‐Based Microgels for Tissue Engineering Applications

Nano Select, EarlyView.
We present a droplet microfluidic approach for preparing porous and irregularly shaped microgels of fibrillar collagen and collagen‐glycosaminoglycan (GAG) copolymer in a continuous oil phase at rates of up to 5500 s−1. ABSTRACT To expand the use of collagen‐based biomaterials beyond their current applications in three‐dimensional (3D) cell culture ...
Ehsan Samiei, Teodor Veres, Axel Günther   +2 more
wiley   +1 more source

Bioinformatics Approach towards Transcriptomics of Filaggrin

Journal of Agromedicine and Medical Sciences (AMS), 2016
Filaggrin, or filaments which combines protein, is one of the important structural protein that works for the development, maintenance, and the formation of the skin as an intact barrier.
Dito Anurogo, Arli Aditya Parikesit
doaj  

Effect of Coptischinensis, Glycyrrhiza uralensis, and Fermented Glycine max Extract as Proactive Therapy for Atopic Dermatitis

Applied Sciences, 2021
The aim of this study was to investigate the effect of the Coptis chinensis, Glycyrrhiza uralensis, and fermented Glycine max (3Hb) extract on lipid barrier recovery and the alleviation of atopic dermatitis (AD). The 3Hb extract was administered to lipid
Beom-Chan Park, Sang-Hyun Ahn, In-Jun Yang, Ki-Bong Kim   +3 more
doaj   +1 more source

Aryl hydrocarbon receptor activation restores filaggrin expression via OVOL1 in atopic dermatitis

Cell Death and Disease, 2017
Filaggrin (FLG) mutation is a well-confirmed genetic aberration in atopic dermatitis (AD). Genome-wide association studies on AD have revealed other susceptibility genes, for example, Ovo-like 1 (OVOL1). Nonetheless, the relation between FLG and OVOL1 is
G. Tsuji, A. Hashimoto-Hachiya, Mari Kiyomatsu-Oda, M. Takemura, F. Ohno, Takamichi Ito, Saori Morino-Koga, C. Mitoma, T. Nakahara, H. Uchi, M. Furue   +10 more
semanticscholar   +1 more source

Atopic eczema [PDF]

, 2016
Atopic eczema is an itchy inflammatory skin disease with a chronic relapsing–remitting course; it has increased in prevalence in recent decades and now affects up to 25% of school-aged children in the developed world and up to 10% of adults.
Deckert, Flohr, Kelleher, Madhok, Nankervis, Rodriguez, Simpson, Williams   +7 more
core   +2 more sources

Az atópiás dermatitis patomechanizmusa [PDF]

, 2018
L
Steuer-Hajdu, Krisztina, Szegedi, Andrea
core   +1 more source

Gene–Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies

Allergy, EarlyView.
Atopic eczema is a complex trait resulting from multiple genetic and environmental factors. This study investigated evidence for interaction between 24 established eczema genetic risk variants and 18 environmental factors. One variant‐environmental pair showed nominally significant interaction in discovery, replication and meta‐analyses: early‐life dog
Marie Standl, Ashley Budu‐Aggrey, Luke J. Johnston, Martina S. Elias, S. Hasan Arshad, Peter Bager, Veronique Bataille, Helena Blakeway, Klaus Bønnelykke, Dorret Boomsma, Ben M. Brumpton, Mariona Bustamante Pineda, Archie Campbell, John A. Curtin, Anders Eliasen, João P. S. Fadista, Bjarke Feenstra, Trine Gerner, Carolina Medina‐Gomez, Sarah Grosche, Kristine B. Gutzkow, Anne‐Sofie Halling, Caroline Hayward, John Henderson, Esther Herrera‐Luis, John W. Holloway, Joukejan Hottenga, Jonathan O’B Hourihane, Chen Hu, Kristian Hveem, Amaia Irizar, Bénédicte Jacquemin, Leon Jessen, Sara Kress, Ramesh J. Kurukulaaratchy, Susanne Lau, Sabrina Llop, Mari Løset, Ingo Marenholz, Dan Mason, Daniel L. McCartney, Mads Melbye, Erik Melén, Camelia Minica, Clare S. Murray, Tamar Nijsten, Luba M. Pardo, Suzanne Pasmans, Craig E. Pennell, Maria R. Rinnov, Gillian Santorelli, Tamara Schikowski, Darina Sheehan, Angela Simpson, Cilla Söderhäll, Laurent F. Thomas, Jacob P. Thyssen, Maties Torrent, Toos van Beijsterveldt, Alessia Visconti, Judith M. Vonk, Carol A. Wang, Cheng‐Jian Xu, Ali H. Ziyab, UK Translational Research Network in Dermatology, BIOMAP Consortium, Adnan Custovic, Paola Di Meglio, Liesbeth Duijts, Carsten Flohr, Alan D. Irvine, Gerard H. Koppelman, Young‐Ae Lee, Nick J. Reynolds, Catherine Smith, Sinéad M. Langan, Lavinia Paternoster, Sara J. Brown   +77 more
wiley   +1 more source

LD Hub:a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis [PDF]

, 2017
Motivation: LD score regression is a reliable and efficient method of using genome-wide association study (GWAS) summary-level results data to estimate the SNP heritability of complex traits and diseases, partition this heritability into functional ...
Anttila, V., Bulik-Sullivan, B., Elsworth, B.L., Erzurumluoglu, A.M., EUMODIC Consortium (Heinrich, J.), Evans, D.M, Finucane, H.K., Gaunt, T.R., Haycock, P.C., Hemani, G., Howe, L., Kemp, J.P., Laurin, C., Neale, B.M., Paternoster, L., Price, A.L., St. Pourcain, B., Tansey, K., Warrington, N.M., Zheng, J.   +19 more
core   +3 more sources

Expression of Filaggrin and its Degradation Products in Human Skin Following Erythemal Doses of Ultraviolet B Irradiation

Acta Dermato-Venereologica, 2017
Epidermal filaggrin level is affected by ultraviolet B irradiation in animal and experimental models. This study examined the effect of ultraviolet B irradiation on epidermal filaggrin and natural moisturizing factors in vivo in healthy adults (n = 22 ...
Stine Simonsen, Jacob P. Thyssen, Steffen Heegaard, Sanja Kezic, Lone Skov   +4 more
doaj   +1 more source