An Aquaporin 3-Notch1 Axis in Keratinocyte Differentiation and Inflammation [PDF]
Aquaporin 3 (AQP3) is an aquaglyceroporin which transports water, glycerol and small solutes across the plasma membrane. Its functions are not limited to fluid transport but also involve the regulation of cell proliferation, migration, skin hydration ...
Chen, Hongxiang+4 more
core +3 more sources
Aging of the Human Lip: Current Knowledge and Clinical Implications
ABSTRACT Background Comprehensive exploration of lip aging remains limited due to anatomical complexity of the structure, with current investigations predominantly focusing on aspects such as dryness management, cheilitis prevention and treatment, and surgical lifts.
Fanghui Sun, Yue Liu, Tao Zhang
wiley +1 more source
Epistasis between FLG and IL4R genes on the risk of allergic sensitization: results from two population-based birth cohort studies [PDF]
Immune-specifc genes as well as genes responsible for the formation and integrity of the epidermal barrier have been implicated in the pathogeneses of allergic sensitization.
A Benedetto De+36 more
core +2 more sources
ABSTRACT Objective Although bioactive compounds from single herbs are extensively explored in cosmetics, the synergistic potential of herbal combinations remains understudied. This study aimed to evaluate the stability of a combined extract of Panax ginseng, Ganoderma lucidum, Cordyceps militaris, and several Asian plants (PGC), and its multifunctional
Wenlong Wang+8 more
wiley +1 more source
Identification of a panel of serum protein markers in early stage of sepsis and its validation in a cohort of patients [PDF]
Background: Sepsis is a life-threatening illness with a challenging diagnosis. Current serum biomarkers are not sensitive enough for diagnosis. With the aim of finding proteins associated with sepsis, serum protein profile was compared between patients ...
Astigarraga Aguirre, María Iciar+7 more
core +2 more sources
Updated insights into the molecular pathogenesis of canine atopic dermatitis
Abstract Atopic dermatitis (AD) is a common and chronic inflammatory skin disease with frequent relapses. The genomics revolution has greatly contributed and revolutionised our knowledge of human AD; understanding the molecular skin fingerprint of AD and associated pathogenic immune pathways has led to preclinical assessments of several novel ...
Frane Banovic
wiley +1 more source
Anti-perinuclear factor compared with the so called "antikeratin" antibodies and antibodies to human epidermis filaggrin, in the diagnosis of arthritides [PDF]
Christian Vincent+5 more
openalex +1 more source
HNRNPK maintains epidermal progenitor function through transcription of proliferation genes and degrading differentiation promoting mRNAs. [PDF]
Maintenance of high-turnover tissues such as the epidermis requires a balance between stem cell proliferation and differentiation. The molecular mechanisms governing this process are an area of investigation.
Chen, Yifang+8 more
core +1 more source
Filaggrin Mutations and Allergic Contact Sensitization [PDF]
In this issue, Novak et al. (2008) provide evidence that filaggrin barrier defects might also predispose to allergic contact dermatitis by allowing greater penetration of chemical haptens. Their report provides a fresh perspective on the issues of contact allergy, nickel sensitization, and stratum corneum defects.
openaire +3 more sources