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Filamentous Hemagglutinin of Bordetella Pertussis : a Key Adhesin with Immunomodulatory Properties?
Future Microbiology, 2014The filamentous hemagglutinin of pathogenic Bordetellae is a prototype of a large two-partner-system-secreted and β-structure-rich bacterial adhesin. It exhibits several binding activities that may facilitate bacterial adherence to airway mucosa and host phagocytes in the initial phases of infection.
Rodrigo, Villarino Romero +2 more
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[The property of filamentous hemagglutinin of Bordetella pertussis].
Zhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology, 1993For the purpose to clarifying the biologically active substance of B. pertussis, we prepared the filamentous hemagglutinin (FHA) from culture supernatant of the strain Tohama phase I and purified it through chromatography columns of hydroxylapatite, fetuin-Sepharose 4B and Sepharose CL 6B.
M P, Chow +7 more
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Vaccine, 1999
Filamentous hemagglutinin (FHA) is an outer-membrane associated adhesin conserved within the genus Bordetella. FHA provides protection against B. pertussis infections in humans and is a component of acellular whooping cough vaccines. Furthermore, FHA serves as a protective antigen in several animal models of infection with B.
D J, Keil +4 more
exaly +3 more sources
Filamentous hemagglutinin (FHA) is an outer-membrane associated adhesin conserved within the genus Bordetella. FHA provides protection against B. pertussis infections in humans and is a component of acellular whooping cough vaccines. Furthermore, FHA serves as a protective antigen in several animal models of infection with B.
D J, Keil +4 more
exaly +3 more sources
Journal of Infectious Diseases, 1994
A pertussis outbreak was studied prospectively in an elementary school with 39 pupils. All had been immunized with at least three doses of Finnish diphtheria-tetanus toxoid-pertussis vaccine. Diagnosis of pertussis was based on culture, polymerase chain reaction results, and EIA serology using filamentous hemagglutinin (FHA), pertussis toxin, and 69 ...
Q, He +6 more
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A pertussis outbreak was studied prospectively in an elementary school with 39 pupils. All had been immunized with at least three doses of Finnish diphtheria-tetanus toxoid-pertussis vaccine. Diagnosis of pertussis was based on culture, polymerase chain reaction results, and EIA serology using filamentous hemagglutinin (FHA), pertussis toxin, and 69 ...
Q, He +6 more
openaire +2 more sources
Journal of Infectious Diseases, 1984
Protective activities of the filamentous hemagglutinin (FHA) and the lymphocytosis-promoting factor (LPF) of Bordetella pertussis were compared by active and passive protection tests with intracerebral or respiratory challenge in mice. Mice immunized twice by intraperitoneal injection of 8 micrograms of FHA or glutaraldehyde-inactivated LPF were ...
M, Oda +3 more
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Protective activities of the filamentous hemagglutinin (FHA) and the lymphocytosis-promoting factor (LPF) of Bordetella pertussis were compared by active and passive protection tests with intracerebral or respiratory challenge in mice. Mice immunized twice by intraperitoneal injection of 8 micrograms of FHA or glutaraldehyde-inactivated LPF were ...
M, Oda +3 more
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Microbial Pathogenesis, 2014
Filamentous hemagglutinin adhesins (FHA) are key factors for bacterial attachment and subsequent cell accumulation on substrates. Here an FHA-like Outer membrane (OM) adhesin of Acinetobacter baumannii ATCC19606(T) was displayed on Escherichia coli. The candidate autotransporter (AT) genes were identified in A. baumannii ATCC19606(T) genome.
Shakiba Darvish Alipour Astaneh +2 more
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Filamentous hemagglutinin adhesins (FHA) are key factors for bacterial attachment and subsequent cell accumulation on substrates. Here an FHA-like Outer membrane (OM) adhesin of Acinetobacter baumannii ATCC19606(T) was displayed on Escherichia coli. The candidate autotransporter (AT) genes were identified in A. baumannii ATCC19606(T) genome.
Shakiba Darvish Alipour Astaneh +2 more
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Contribution of Fimbria and Filamentous hemagglutinin in Bordetella Adherence and Immune Suppression
2015Pertussis, or whooping cough, is a highly contagious respiratory disease caused by Bordetella pertussis. Recent changes to the vaccine against B. pertussis have led to the re-emergence of this disease. Given the re-emergence of pertussis, it is critical to understand Bordetella pathogenesis.
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4563303 Method for purification of filamentous hemagglutinin
Biotechnology Advances, 1986openaire +2 more sources
Filamentous Hemagglutinin of Bordetella Pertussis : a Key Adhesin with Immunomodulatory Properties?
Future Microbiology, 2014Radim Osicka, Peter Sebo
exaly