Results 131 to 140 of about 10,264 (194)

Identification of a novel splice variant form of the influenza A virus M2 ion channel with an antigenically distinct ectodomain [PDF]

, 2012
Segment 7 of influenza A virus produces up to four mRNAs. Unspliced transcripts encode M1, spliced mRNA2 encodes the M2 ion channel, while protein products from spliced mRNAs 3 and 4 have not previously been identified.
Digard, Paul, Firth, Andrew E., Fodor, Ervin, Gog, Julia R., Hutchinson, Edward C., Jagger, Brett W., Kang, Zi H., Kash, John C., Robb, Nicole, Schwartzman, Louis M., Stuart, Amanda D., Taubenberger, Jeffery K., Wise, Helen M.   +12 more
core   +4 more sources

FHA-mediated cell-substrate and cell-cell adhesions are critical for Bordetella pertussis biofilm formation on abiotic surfaces and in the mouse nose and the trachea.

PLoS ONE, 2011
Bordetella spp. form biofilms in the mouse nasopharynx, thereby providing a potential mechanism for establishing chronic infections in humans and animals. Filamentous hemagglutinin (FHA) is a major virulence factor of B. pertussis, the causative agent of
Diego O Serra, Matt S Conover, Laura Arnal, Gina Parise Sloan, María E Rodriguez, Osvaldo M Yantorno, Rajendar Deora   +6 more
doaj   +1 more source

Multivalent interactions between fully glycosylated influenza virus hemagglutinins mediated by glycans at distinct N-glycosylation sites

npj Viruses
The hemagglutinin (HA) glycoprotein of influenza virus binds host cell receptors and mediates viral entry. Here we present cryo-EM structures of fully glycosylated HAs from H5N1 and H5N8 influenza viruses. We find that the H5N1 HA can form filaments that
Ruofan Li, Jingjing Gao, Lin Wang, Miao Gui, Ye Xiang   +4 more
doaj   +1 more source

Specific Lung Mucosal and Systemic Immune-Responses After Oral Immunization of Mice with Salmonella-Typhimurium-Aroa, Salmonella-Typhi Ty21a, and Invasive Escherichia-Coli Expressing Recombinant Pertussis Toxin S1 Subunit [PDF]

, 1992
Pertussis toxin (PT) is considered an essential protective component for incorporation into new generation vaccines against Bordetella pertussis, the causative agent of whooping cough.
Guzman, Carlos A., Rohde, Manfred, Timmis, Kenneth N., Walker, Mark J.   +3 more
core  

Antibody-Responses in the Serum and Respiratory-Tract of Mice Following Oral Vaccination with Liposomes Coated with Filamentous Hemagglutinin and Pertussis Toxoid [PDF]

, 1993
Mice were orally vaccinated with liposomes coated with filamentous hemagglutinin (FHA) and detoxified pertussis toxin (PT) of Bordetella pertussis. FHA- and PT-specific immunoglobulin G (IgG) was detected in serum, and both IgG and IgA were detected in ...
Guzman, Carlos A., Molinari, Gabriella, Fountain, Michael W., Rohde, Manfred, Timmis, Kenneth N., Walker, Mark J.   +5 more
core  

Cultivation of \u3cem\u3eTropheryma whipplei\u3c/em\u3e from Cerebrospinal Fluid [PDF]

, 2003
Whipple disease (WD) is a systemic disorder caused by the bacterium Tropheryma whipplei. Since the recognition of a bacterial etiology in 1961, many attempts have been made to cultivate this bacterium in vitro.
Fredricks, David N., Herbay, Axel von, Kosek, Jon C., Maiwald, Matthias, Ouverney, Cleber C., Relman, David A.   +5 more
core   +1 more source

The Role of Bordetella Infections in Patients with Acute Exacerbation of Chronic Bronchitis [PDF]

, 2018
: Background: : Acute exacerbations of chronic bronchitis (AECB) are associated with a variety of viral and bacterial infectious agents, some of which are potentially preventable by immunization. Bordetella pertussis, which causes whooping cough, has not
Bonhoeffer, J., Bär, G., Heininger, U., Riffelmann, M., Solèr, M.   +4 more
core  

Serologic evidence of pertussis infection in vaccinated Iranian children [PDF]

, 2012
Background: It seems that the incidence of pertussis-like illnesses is considerably increasing despite the wide coverage of immunization with the whole cell pertussis vaccine.
Arjmand, Reza., Gholinejad, Zari., Joulaei, Hassan., Karimi, Abdollah., Kheirkhah, Taherh., Moghadami, Mohsen., Sanaei Dashti, Anahita., Shiva, Farideh.   +7 more
core   +2 more sources

Quantitative bead-based multiplex assay for simultaneous determination of IgG concentrations of pertussis toxin, filamentous hemagglutinin, pertactin, diphtheria, tetanus, Haemophilus influenzae b, and hepatitis B in human serum samples. [PDF]

Front Immunol
Rathod V, Katke S, Patil S, Bhandare S, Kadam L, Gautam M, Gumma P, Kumar KM, Hassall L, Asokanathan C, Douglas-Bardsley A, Markey K, Gupta S, Rao H, Parekh S, Pujari P, Sharma H, Shaligram U, Gairola S.   +18 more
europepmc   +1 more source

Mucosal and systemic immune responses elicited by recombinant Lactococcus lactis expressing a fusion protein composed of pertussis toxin and filamentous hemagglutinin from Bordetella pertussis. [PDF]

Microb Pathog, 2018
Torkashvand A, Bahrami F, Adib M, Ajdary S.   +3 more
europepmc   +1 more source