Results 41 to 50 of about 76,316 (279)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

BiSON data-file formats [PDF]

, 2003
The RAWDATA, DAT, CMP, SM1, DATA, IZDATA, BBC, and RES file formats are ...
Miller, Brek A., Elsworth, Yvonne, Hale, Steven J.; id_orcid, Allison, John, Hale, Steven J., Chaplin, William J.   +5 more
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

A Classification of File Formats for Animation [PDF]

, 1998
This paper proposes a classification of existing file formats for computer animation. File formats for computer animation store and describe the evolution of virtual scenes over time. They permit applications, which produce animating scenes, to share and
Gene Lee
core  

Enabling FAIR data in Earth and environmental science with community-centric (meta)data reporting formats

Scientific Data, 2022
Research can be more transparent and collaborative by using Findable, Accessible, Interoperable, and Reusable (FAIR) principles to publish Earth and environmental science data.
Robert Crystal-Ornelas, Charuleka Varadharajan, Dylan O’Ryan, Kathleen Beilsmith, Benjamin Bond-Lamberty, Kristin Boye, Madison Burrus, Shreyas Cholia, Danielle S. Christianson, Michael Crow, Joan Damerow, Kim S. Ely, Amy E. Goldman, Susan L. Heinz, Valerie C. Hendrix, Zarine Kakalia, Kayla Mathes, Fianna O’Brien, Stephanie C. Pennington, Emily Robles, Alistair Rogers, Maegen Simmonds, Terri Velliquette, Pamela Weisenhorn, Jessica Nicole Welch, Karen Whitenack, Deborah A. Agarwal   +26 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Abstract File-Formats for Preservation: Evaluating the Long-Term Stability of File-Formats [PDF]

, 2007
While some file-formats become unreadable after short periods, others remain interpretable over a long-term. Among the over 1.000 file-formats, some are better and some are less suited for long-term preservation. A standardized process for evaluating the
Harald Krottmaier, Carl Rauch, H. Krottmaier, Klaus Tochtermann, K. Tochtermann, C. Rauch   +5 more
core  

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

ERPANET-Seminar: File Formats for Preservation [PDF]

, 2004
Das nächste Seminar von ERPANET findet am 10. und 11. Mai 2004 in der Österreichischen Nationalbibliothek statt. Thema sind "File Formats for Preservation". Das provisorische Programm: Montag, 10.
Richterb
core  

Neo: an object model for handling electrophysiology data in multiple formats

Frontiers in Neuroinformatics, 2014
Neuroscientists use many different software tools to acquire, analyse and visualise electrophysiological signals. However, incompatible data models and file formats make it difficult to exchange data between these tools.
Samuel eGarcia, Domenico eGuarino, Florent eJaillet, Todd R Jennings, Robert ePröpper, Philipp L Rautenberg, Chris eRodgers, Andrey eSobolev, Thomas eWachtler, Pierre eYger, Andrew P Davison   +10 more
doaj   +1 more source