Results 41 to 50 of about 366,495 (268)

HTTP adaptive streaming with media fragment URIs [PDF]

, 2011
HTTP adaptive streaming was introduced with the general idea that user agents interpret a manifest file (describing different representations and segments of the media); where-after they retrieve the media content using sequential HTTP progressive ...
Mannens, Erik, Van de Walle, Rik, Van Deursen, Davy, Van Lancker, Wim   +3 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Enabling FAIR data in Earth and environmental science with community-centric (meta)data reporting formats

Scientific Data, 2022
Research can be more transparent and collaborative by using Findable, Accessible, Interoperable, and Reusable (FAIR) principles to publish Earth and environmental science data.
Robert Crystal-Ornelas, Charuleka Varadharajan, Dylan O’Ryan, Kathleen Beilsmith, Benjamin Bond-Lamberty, Kristin Boye, Madison Burrus, Shreyas Cholia, Danielle S. Christianson, Michael Crow, Joan Damerow, Kim S. Ely, Amy E. Goldman, Susan L. Heinz, Valerie C. Hendrix, Zarine Kakalia, Kayla Mathes, Fianna O’Brien, Stephanie C. Pennington, Emily Robles, Alistair Rogers, Maegen Simmonds, Terri Velliquette, Pamela Weisenhorn, Jessica Nicole Welch, Karen Whitenack, Deborah A. Agarwal   +26 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

A Manufacturer Design Kit for Multi-Chip Power Module Layout Synthesis [PDF]

, 2017
The development of Multi-Chip Power Modules (MCPMs) has been a key factor in recent advancements in power electronics technologies. MCPMs achieve higher power density by combining multiple power semiconductor devices into one package.
Main, Jonathan
core   +2 more sources

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

HUDDL for description and archive of hydrographic binary data [PDF]

, 2014
Many of the attempts to introduce a universal hydrographic binary data format have failed or have been only partially successful. In essence, this is because such formats either have to simplify the data to such an extent that they only support the ...
Calder, Brian R., Masetti, Giuseppe
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Decompilation from Selected Object File Formats [PDF]

, 2016
Objektové súbory obsahujú strojový kód, ktorý môže byť vykonaný procesorom. Každý objektový súbor má formát, ktorý popisuje jeho štruktúru. Pre vykonanie spätného prekladu je nutné súbor spracovať a previesť dáta do vnútornej reprezentácie spätného ...
Bandzi, Michal
core