Results 91 to 100 of about 35,622 (198)
CD93—An emerging vascular target in cancer therapy
British Journal of Pharmacology, EarlyView.Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira +3 more
wiley +1 more source
FiloDetect: automatic detection of filopodia from fluorescence microscopy images
, 2015 Background Filopodia are small cellular projections that help cells to move through and sense their environment. Filopodia play crucial roles in processes such as development and wound-healing.
Lee, Jonathan M +3 more
core +1 more source
Filopodia and their links with membrane traffic and cell adhesion. [PDF]
, 2019 Filopodia are dynamic, narrow, plasma membrane protrusions filled with bundled actin filaments. Fresh actin monomers are incorporated at the tips furthest away from the cell body, where barbed end polymerases such as formins and Ena/VASP proteins are ...
core +2 more sources
Journal of Extracellular VesiclesExtracellular vesicles (EVs) are shed from the plasma membrane, but the regulation and function of these EVs remain unclear. We found that oxidative stress induced by H2O2 in Hela cells stimulated filopodia formation and the secretion of EVs.
Zainuddin Quadri +10 more
doaj +1 more source
eLifeHuman Papillomaviruses (HPVs) are the underlying cause of several types of cancer; albeit, they are mostly known for their association with cervical carcinoma. The virions reach their target cells through a break in the epithelial barrier.
Annika Massenberg +6 more
doaj +1 more source
Inception Mechanisms of Tunneling Nanotubes
Cells, 2019 Tunneling nanotubes (TNTs) are thin membranous tubes that interconnect cells, representing a novel route of cell-to-cell communication and spreading of pathogens. TNTs form between many cell types, yet their inception mechanisms remain elusive. We review
Mitja Drab +3 more
doaj +1 more source
Cell‐Migration Visualization: Task Taxonomy, Systematic Review and Research Agenda
Computer Graphics Forum, EarlyView.We present an expert‐validated task taxonomy for cell migration analysis and a PRISMA‐based systematic review that maps visualization tools to the tasks they support and the techniques they employ. This synthesis identifies current gaps and outlines opportunities for future research in cell migration visualization.
Ana Carla Correia +3 more
wiley +1 more source
Emerging Roles of PSTPIP2 in Autoimmunity: From Mechanism to Therapeutic Implications
Immunology, EarlyView.PSTPIP2 acts as a key brake on myeloid inflammation by suppressing IL‐1β‐driven signalling, macrophage dysregulation and inflammation‐associated bone remodelling. Its emerging roles in CRMO/CMO, rheumatoid arthritis, SAPHO syndrome and bullous pemphigoid support its potential as a biomarker and therapeutic target.
Erdong Zhang +9 more
wiley +1 more source
Following the footprints of variability during filopodia growth [PDF]
, 2021 Filopodia are actin-built finger-like dynamic structures that protrude from the cell cortex. These structures can sense the environment and play key roles in migration and cell-cell interactions.
Gueron, Geraldine +4 more
core
Huntingtin as an Actin Organizer: Structural and Functional Insights
Cytoskeleton, EarlyView.
M. Capizzi, S. Humbert
wiley +1 more source