Results 81 to 90 of about 35,622 (198)

Activating Transcription Factor 4 (ATF4) Modulates Post-synaptic Development and Dendritic Spine Morphology

open access: yesFrontiers in Cellular Neuroscience, 2014
The ubiquitously expressed activating transcription factor 4 (ATF4) has been variably reported to either promote or inhibit neuronal plasticity and memory.
Jin eLiu   +3 more
doaj   +1 more source

Peptide Terminated Polymer Brush Nanomaterials for Label‐Free Separation of Cancer Cells Based on Relative Adhesion

open access: yesSmall, EarlyView.
Horan et al. demonstrate that RGD peptide‐functionalized poly(ethylene glycol) brush films synthesized in polydimethylsiloxane microfluidic channels by surface‐initiated atom transfer radical polymerization enable label‐free separation of melanoma and ovarian cancer cells based on differential integrin expression.
Stephen Horan   +6 more
wiley   +1 more source

Contribution of Filopodia to Cell Migration: A Mechanical Link between Protrusion and Contraction

open access: yesInternational Journal of Cell Biology, 2010
Numerous F-actin containing structures are involved in regulating protrusion of membrane at the leading edge of motile cells. We have investigated the structure and dynamics of filopodia as they relate to events at the leading edge and the function of ...
Fei Xue   +2 more
doaj   +1 more source

Influence of Micropatterned Grill Lines on Entamoeba histolytica Trophozoites Morphology and Migration

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Entamoeba histolytica, the causal agent of human amoebiasis, has two morphologically different phases: a resistant cyst and a trophozoite responsible for the invasion of the host tissues such as the colonic mucosa and the intestinal epithelium. During in
Francisco Sierra-López   +5 more
doaj   +1 more source

Surface‐Functionalized Poly(2‐Oxazoline)‐Based Grids Produced by Two‐Photon Polymerization as 3D‐Structured Hydrogels Promoting Cell Adhesion

open access: yesSmall, EarlyView.
Sidechain‐functionalized poly(2‐oxazoline) cross‐linkers were utilized to print grids with varying mesh sizes by two‐photon polymerization (2PP grids). The amino‐functionalized hydrogels were subsequently used to covalently couple the RGD‐containing peptide sequence GCWRGDSP (RGD) to the amino groups in the side chains. In cell adhesion tests with L929
Tim Hoffmann   +11 more
wiley   +1 more source

Geometric structure of filopodia model.

open access: yes, 2015
A) Roots of filopodia are attached to the cellular membrane (six blue arrows), and the 1st and last AM (acto-myosin) compartments are attached to the cellular membrane and the filopodial tip, respectively (yellow arrows).
Yaron R. Silberberg (803540)   +4 more
core   +1 more source

A lysosome‐targeted ultra‐sensitive viscosity probe for monitoring viscosity alterations during chemotherapy

open access: yesSmart Molecules, EarlyView.
A novel chemosensing platform based on a molecular rotor architecture is established for specific, dynamic detection of lysosomal viscosity. The platform allows real‐time tracking of lysosomal viscosity fluctuations induced by various chemotherapeutic agents, highlighting its significant potential as a powerful tool for early cancer diagnostics and ...
Haoyang Song   +6 more
wiley   +1 more source

Halting the Progression of Acute Kidney Injury: A Tubular‐Inspired Reusable Detoxifier Against Protein‐Bound Uremic Toxins and Oxidative Stress

open access: yesSusMat, EarlyView.
This graphical ToC illustrates a tubular‐inspired detoxifier (SDCMs–DS) that halts acute kidney injury progression. Inspired by proximal tubular epithelial cells (PTECs), the biomimetic design combines dissociation‐adsorption clearance of protein‐bound uremic toxins (PBUTs) with antioxidant protection. During hemoperfusion, danshensu (DS) released from
Yilin Wang   +12 more
wiley   +1 more source

Activity-induced filopodia form at the presynapse and enclose SV fusion.

open access: yes
The combination of synaptic structural stability and functional plasticity is a recognized feature of the nervous system. This dichotomy is possible because the processes involved in neuronal information processing, such as receiving and transducing ...
Ivanova, Daniela
core   +1 more source

Characterization of AQP9-induced filopodia.

open access: yes, 2013
(A) Representative confocal images of HEK-293 cells transfected with tagRFP-AQP9 or empty vector together with GFP-Mem to label the membrane. Intensities have been adjusted linearly to visualize the relative expression and localization of both ...
Anastasia Bolshakova (398118)   +4 more
core   +1 more source

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