Results 121 to 130 of about 645,297 (298)
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
The impact of hormonal contraceptives on blood pressure, urinary albumin excretion and glomerular filtration rate [PDF]
Jarir At Thobari +5 more
openalex +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
PHOTOCATALYSIS–MEMBRANE SEPARATION COUPLING REACTOR: REMOVAL OF ORGANIC POLLUTANTS FROM WATER
This work reports the photodegradation process of methylene blue in a membrane photoreactor by using TiO2 as the photocatalyst and phosphate microfiltration membrane as separation barrier recovery and recycle the photocalysts particles.
Noureddine Elbaraka +6 more
doaj
Filtration and splitting of the Hodge bundle on the non-varying strata of quadratic differentials [PDF]
Dawei Chen, Yu Fei
openalex +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source

