Results 41 to 50 of about 4,342 (172)

Reciprocal Packaging of the Main Structural Proteins of Type 1 Fimbriae and Flagella in the Outer Membrane Vesicles of “Wild Type” Escherichia coli Strains

Frontiers in Microbiology, 2021
Fundamental aspects of outer membrane vesicle (OMV) biogenesis and the engineering of producer strains have been major research foci for many in recent years.
Sarah A. Blackburn, Mark Shepherd, Gary K. Robinson   +2 more
doaj   +1 more source

Role of SCFAs for Fimbrillin-Dependent Biofilm Formation of Actinomyces oris

Microorganisms, 2018
Actinomyces oris expresses type 1 and 2 fimbriae on the cell surface. Type 2 fimbriae mediate co-aggregation and biofilm formation and are composed of the shaft fimbrillin FimA and the tip fimbrillin FimB.
Itaru Suzuki, Takehiko Shimizu, Hidenobu Senpuku   +2 more
doaj   +1 more source

Computational Studies on Recent Congeners of Fluoroquinolones and Nitroimidazoles for Their Use in Periodontal Therapy

Journal of Pharmacy and Bioallied Sciences
Background: Periodontitis is a slow progressing infection and has profound systemic implications. The influence of various therapeutic drugs to inhibit inflammation and promote bone regeneration has been studied.
Prabhu Manickam Natarajan
doaj   +1 more source

Type I fimbriae subunit fimA enhances Escherichia coli biofilm formation but affects L-threonine carbon distribution

Frontiers in Bioengineering and Biotechnology, 2022
The biofilm (BF) provides favorable growth conditions to cells, which has been exploited in the field of industrial biotechnology. Based on our previous research works on type I fimbriae for the biosynthesis of L-threonine (LT) in Escherichia coli, in ...
Qingguo Liu, Qingguo Liu, Jiaqing Zhu, Na Liu, Wenjun Sun, Bin Yu, Huanqing Niu, Dong Liu, Pingkai Ouyang, Hanjie Ying, Yong Chen, Gulin Zhao, Tianpeng Chen   +12 more
doaj   +1 more source

Immunization with FimA protects against Streptococcus parasanguis endocarditis in rats [PDF]

Infection and Immunity, 1997
FimA, a surface-associated protein of Streptococcus parasanguis, is associated with initial colonization of damaged heart tissue in an endocarditis model (D. Burnette-Curley, V. Wells, H. Viscount, C. Munro, J. Fenno, P. Fives-Taylor, and F. Macrina, Infect. Immun. 63:4669-4674, 1995).
H B, Viscount, C L, Munro, D, Burnette-Curley, D L, Peterson, F L, Macrina   +4 more
openaire   +2 more sources

Distribution of Porphyromonas gingivalis fimA genotypes in primary endodontic infections [PDF]

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2010
Long fimbriae (FimA) are important virulence factors of Porphyromonas gingivalis. Based on the diversity of the fimA gene, this species is classified into 6 genotypes. This study surveyed samples from primary endodontic infections for the presence of these P.
Isabela N, Rôças, José F, Siqueira
openaire   +2 more sources

Construction and characterization of a fimA mutant of Porphyromonas gingivalis [PDF]

Infection and Immunity, 1994
Although fimbriae of Porphyromonas gingivalis have been implicated as playing a major role in adherence to gingival tissue surfaces, no conclusive genetic evidence has yet been obtained. The fimA gene, the determinant for the major fimbrial subunit protein, was cloned and sequenced (D. P. Dickinson, M. A. Kubiniec, F. Yoshimura, and R. J.
N, Hamada, K, Watanabe, C, Sasakawa, M, Yoshikawa, F, Yoshimura, T, Umemoto   +5 more
openaire   +2 more sources

CAT‐BLAST: Engineered bacteria for robust targeting and elimination of cancer‐associated fibroblasts

iMeta, EarlyView.
Cancer‐associated fibroblasts (CAFs) construct a protective stromal barrier that promotes tumor growth and resistance to therapy. To dismantle this, we developed CAT‐BLAST, an engineered bacterial platform designed to potently eliminate these cells. We engineered a safe, high‐expression E.
Mengdi Xu, Ehsan Hashemi, Hui Gao, Qumar Zaman, Yi Ma, Jufang Wang, Wenjun Mao, Zhuobin Liang   +7 more
wiley   +1 more source

Clinical recommendations for early identification of patients with open‐angle glaucoma at higher risk of low adherence to topical treatment: An Italian Delphi consensus

Acta Ophthalmologica, EarlyView.
Abstract Purpose It is important for clinicians to identify patients with glaucoma at higher risk of poor adherence to topical therapy at an early stage to prescribe alternative treatments. An expert‐based set of statements was developed to assist clinicians in the early identification of patients at high risk of low adherence and subsequent poorer ...
Roberto G. Carassa, Giovanni Pomponio, Luca Agnifili, Antonio Maria Fea, Michele Iester, Giorgio Marchini, Enrico Martini, Stefano Miglior, Francesco Oddone, Luca Rossetti, Matteo Sacchi, Carlo Enrico Traverso, Michele Figus   +12 more
wiley   +1 more source

HDACi vorinostat protects muscle from degeneration after acute rotator cuff injury in mice

Bone & Joint Research
Aims: Rotator cuff (RC) injuries are characterized by tendon rupture, muscle atrophy, retraction, and fatty infiltration, which increase injury severity and jeopardize adequate tendon repair.
Lara Gil-Melgosa, Rafael Llombart-Blanco, Leire Extramiana, Isabel Lacave, Gloria Abizanda, Estibaliz Miranda, Xabier Agirre, Felipe Prósper, Antonio Pineda-Lucena, Juan Pons-Villanueva, Ana Pérez-Ruiz   +10 more
doaj   +1 more source