Results 61 to 70 of about 31,980 (224)

Functional Analysis of the Chaperone-Usher Fimbrial Gene Clusters of Salmonella enterica serovar Typhi

Frontiers in Cellular and Infection Microbiology, 2018
The human-specific pathogen Salmonella enterica serovar Typhi causes typhoid, a major public health issue in developing countries. Several aspects of its pathogenesis are still poorly understood. S.
Karine Dufresne, Julie Saulnier-Bellemare, France Daigle   +2 more
doaj   +1 more source

Expression of the short fimbriae ofPorphyromonas gingivalisis regulated in oral bacterial consortia [PDF]

FEMS Microbiology Letters, 2006
The Mfa1 protein of Porphyromonas gingivalis is the structural subunit of the short fimbriae and mediates coadhesion between P. gingivalis and Streptococcus gordonii. We utilized a promoter-lacZ reporter construct to examine the regulation of mfa1 expression in consortia with common oral plaque bacteria.
Yoonsuk, Park, Chloe E, James, Fuminobu, Yoshimura, Richard J, Lamont   +3 more
openaire   +2 more sources

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

The structure of the PapD-PapGII pilin complex reveals an open and flexible P5 pocket [PDF]

, 2012
P pili are hairlike polymeric structures that mediate binding of uropathogenic Escherichia coli to the surface of the kidney via the PapG adhesin at their tips.
Baga M, Bann JG, Barnhart MM, Dodson KW, Dodson KW, Doublie S, Gong M, Griebling TL, Henderson NS, Hess B, Holmgren A, Hooton TM, Hultgren SJ, Hung DL, Hung DL, Hung DL, Jacob-Dubuisson F, Jones CH, Justice SS, Kabsch W, Knight SD, Kuehn MJ, Kuehn MJ, Leslie A, Martinez JJ, Munera D, Nishiyama M, Painter J, Pellecchia M, Phan G, Remaut H, Remaut H, Roberts JA, Roberts JA, Rose RJ, Sauer FG, Sauer FG, Sauer FG, Saulino ET, Saulino ET, Sheldrick GM, Slonim LN, Striker R, Stromberg N, Verger D, Verger D, Volkan E, Wright KJ, Zavialov AV   +48 more
core   +2 more sources

Chimeric FimH adhesin of type 1 fimbriae: a bacterial surface display system for heterologous sequences [PDF]

Microbiology, 1995
The FimH adhesin of type 1 fimbriae has been tested as a display system for heterologous protein segments on the surface of Escherichia coli. This was carried out by introduction of restriction site handles (BglII sites) in two different positions in the fimH gene, followed by in-frame insertion of heterologous DNA segments encoding two reporter ...
Pallesen, L, Poulsen, LK, Christiansen, Gunna, Klemm, P   +3 more
openaire   +3 more sources

Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications

Journal of Periodontal Research, EarlyView.
Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu, Yuan Chen, Mario Romandini, Håvard Jostein Haugen, Sašo Ivanovski   +4 more
wiley   +1 more source

Proteus sp. – an opportunistic bacterial pathogen – classification, swarming growth, clinical significance and virulence factors [PDF]

, 2013
The genus Proteus belongs to the Enterobacteriaceae family, where it is placed in the tribe Proteeae, together with the genera Morganella and Providencia. Currently, the genus Proteus consists of five species: P. mirabilis, P. vulgaris, P.
Drzewiecka, Dominika, Kwil Iwona, Maszewska Agnieszka, Moryl, Magdalena, Ostrowska Kinga, Palusiak, Agata, Różalski, Antoni, Siwinska, Malgorzata, Staçzek Paweł, Torzewska, Agnieszka, Zabłotni, Agnieszka   +10 more
core   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Porphyromonas gingivalis fimbriae

Journal of Oral Microbiology, 2013
Marginal periodontitis is not a homogeneous disease but is rather influenced by an intricate set of host susceptibility differences as well as diversities in virulence among the harbored organisms. It is likely that clonal heterogeneity of subpopulations
Morten Enersen, Kazuhiko Nakano, Atsuo Amano   +2 more
doaj   +1 more source

Unraveling the molecular basis of subunit specificity in P pilus assembly by mass spectrometry [PDF]

, 2008
P pili are multisubunit fibers essential for the attachment of uropathogenic Escherichia coli to the kidney. These fibers are formed by the noncovalent assembly of six different homologous subunit types in an array that is strictly defined in terms of ...
A. E. Ashcroft, Benesch, Choudhury, D. Verger, Dodson, E. Paci, G. Waksman, Gong, H. Remaut, Jacob-Dubuisson, Jacob-Dubuisson, Jones, R. J. Rose, Remaut, Remaut, Roberts, Rose, S. E. Radford, Sauer, Sauer, Sauer, Saulino, Soto, Stathopoulos, T. Daviter, Thanassi, Thanassi, Verger, Zavialov   +28 more
core   +2 more sources