Results 81 to 90 of about 4,839,506 (299)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Numerical Treatment Of The Bounded-Control LQR Problem By Updating The Final Phase Value

open access: yesIEEE Latin America Transactions, 2016
A novel approach has been developed for approximately solving the constrained LQR problem, based on updating the final state and costate of an unrestricted related regular problem, and the switching times (when the control meets the constraints). The main result is the expression of a suboptimal control in feedback form by using some corresponding ...
Costanza, Vicente   +2 more
openaire   +2 more sources

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Complete Rank Theorem in Advanced Calculus and Frobenius Theorem in Banach Space [PDF]

open access: yes, 2015
The application of generalized inverses is usually neglected in pure mathematical research. However, it is very effective for this paper. We expand the famous matrix rank theorem due to R. Penrose to operators between Banach paces.
Ma, Jipu
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Filter regularization for final value fractional diffusion problem with deterministic and random noise

open access: yesComputers & Mathematics with Applications, 2017
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Tuan, Nguyen Huy   +3 more
openaire   +1 more source

The Energy of a Dynamical Wave-Emitting System in General Relativity [PDF]

open access: yes, 2003
The problem of energy and its localization in general relativity is critically re-examined. The Tolman energy integral for the Eddington spinning rod is analyzed in detail and evaluated apart from a single term.
Cooperstock, F. I., Tieu, S.
core   +1 more source

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

Shared Bikes Scheduling Under Users’ Travel Uncertainty

open access: yesIEEE Access, 2020
With the rise of green concept, shared bikes are booming. The accompanying unbalanced scheduling problem is a scientific problem that needs to be solved urgently. Aiming at the problem of shared bikes scheduling with travel uncertainty, a multi-objective
Zhi-Yong Zhang, Xiao Zhang
doaj   +1 more source

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