Results 41 to 50 of about 711,500 (260)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Économie et politique éducative en Amérique latine
Revue Internationale d’Éducation de Sèvres, 1999 In Latin America, the economic dimension is beginning to be taken into account in elaborating and directing educational policies. This is shown by the changes which are appearing in a certain number of countries in this region and in particular in Chile,
Robert W. McMeekin
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
A la recherche de l'efficacité
Revue Internationale d’Éducation de Sèvres, 1999 In a complex educational system, in which power is shared between the federal State, the regions, and the local authorities, Switzerland still needs to debate on the quality of its higher education system.
Edo Poglia
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Le financement de l’enseignement supérieur en Algérie : Contraintes et perspectives
Revue des Sciences Humaines, 2005 L’enseignement supérieur a connu, depuis l’indépendance, la croissance la plus rapide du système éducatif. Cette croissance rapide s’explique, à la fois, par la garantie d’un emploi dans le secteur étatique pour les diplômés de l’enseignement supérieur ...
Youcef BERKANE
doaj
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Academic Finance, 2016 Cet article a pour objectif d'analyser dans quelle mesure la théorie du financement hiérarchique (Pecking order theory) est d'une application pertinente pour les entreprises familiales.
faten CHIBANI LTAIEF +1 more
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Appel pour une allocation intelligente dans le financement du système de santé au Cameroun
The Pan African Medical Journal, 2011 Le Cameroun utilise un système de budgétisation historique et une approche en top - down en pour allouer ses ressources. Le pays compte 175 districts de santé présentant de fortes disparités de nature épidémiologique, économique, géographique et ...
Isidore Sieleunou
doaj +1 more source