Results 61 to 70 of about 4,520 (218)

PROTOCOL: Financial coaching for enhancing household finances and health/well‐being: A systematic review and meta‐analysis

open access: yesCampbell Systematic Reviews
This is the protocol for a Campbell systematic review. The objectives are as follows. The primary objective of this review is to answer the following research questions: (1) What is the extent of financial coaching intervention research? (2) What are the
Julie Birkenmaier   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

FINANCIAL STRESS IN COLLEGE STUDENTS: EXAMINING GENDER DIFFERENCES IN RELATION TO SOCIO-ECONOMIC FACTORS

open access: yesEducation. Innovation. Diversity
Rising concerns about student financial well-being and financial pressures on them highlight the need to examine the financial stress of students in higher education and how it varies by gender and socio-economic status.
Līga Roķe-Reimate   +4 more
doaj   +1 more source

Economic abuse between intimate partners in Australia: prevalence, health status, disability and financial stress

open access: yesAustralian and New Zealand Journal of Public Health, 2017
Objective: Economic abuse is a form of domestic violence that has a significant impact on the health and financial wellbeing of victims, but is understudied.
Jozica Kutin, Roslyn Russell, Mike Reid
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

AN OVERVIEW OF FISCAL CONSOLIDATION PROCESS IN THE EUROPEAN UNION

open access: yesStudies and Scientific Researches: Economics Edition, 2014
This paper aims to explore, based on theoretical and empirical research in the field and on data available on Eurostat and European Commission, in the context of financial significant imbalances and thus of the financial stress in the EU countries and ...
Iulia Andreea Bucur, Mircea Muntean
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Heterogeneous Effects of Unconventional Monetary Policy on Financial Stability in the Euro Area [PDF]

open access: yesСовременная Европа
The European Central Bank (ECB) has been using unconventional monetary policy (UMP) since 2009, but the set of measures and their scale have varied significantly over the years. Until 2022, the measures were stimulatory and gradually expanded to increase
Oscar Mukhametov
doaj   +1 more source

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