Results 71 to 80 of about 4,520 (218)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

The Financial Stress Index: Identification of Systemic Risk Conditions

Risks, 2015
This paper develops a financial stress measure for the United States, the Cleveland Financial Stress Index (CFSI). The index is based on publicly available data describing a six-market partition of the financial system comprising credit, funding, real ...
Mikhail V. Oet, John M. Dooley, Stephen J. Ong   +2 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Intrinsic motivation, future orientation, and financial stress: a student-centered model of metaverse classroom adoption in low-income contexts

Cogent Education
The rapid rise of immersive technologies has placed metaverse-based classrooms at the center of higher education innovation. Yet, little is known about how students in low-income contexts perceive and adopt these platforms, particularly when motivation ...
Mousa Al-Kfairy, Omar Alfandi, Saed Alrabaee   +2 more
doaj   +1 more source

The silent crisis: Economic burden of genetic disease diagnosis in lowand middle-income countries (LMICs) [PDF]

Scripta Medica
Genetic disorders, although secondary to infectious and non-communicable diseases in the global health priority agenda, are an important drain, albeit ill-defined, on the economies of lowand middle-income countries (LMICs) and on their health resources ...
Baig Atif Amin, Thein Khin Hla Hla, Htoo Phone Myint, Anwar Khawar, Chopra Hitesh, Chopra Shivani   +5 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Young Families' Financial Stress: The Importance of Financial Management Behavior with Income as Control Variable

Indigenous
. Achieving financial well-being is a universal aspiration among families. However, data indicate that numerous families in Indonesia continue to experience financial stress, partially attributed to financial management behavior.
Fajrina Noor Islami, Theda Renanita
doaj   +1 more source

Financial burden of glycemic control: a single-center retrospective study of diabetes costs in South Korean patients [PDF]

The Korean Journal of Internal Medicine
Background/Aims The impact of glycemic control on healthcare costs is a critical research area. In this study, we aimed to evaluate the relationship between hemoglobin A1c (HbA1c) levels and healthcare costs, including out-of-pocket (OOP) expenses and ...
Han-Sang Baek, Sungju Kim, Dong-Jun Lim, Chul-Min Kim, Tae Seo Sohn, Sungrae Kim   +5 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Evaluation of conflict hazard and financial risk in the E7 economies’ capital markets [PDF]

Zbornik radova Ekonomskog fakulteta u Rijeci : časopis za ekonomsku teoriju i praksu, 2013
The purpose of this research is to examine the interaction between financial stress and conflict risk having impacts on fi nancial instruments in capital markets within an interdisciplinary frame.
Ümit Hacıoğlu, Hasan Dinçer
doaj