Results 71 to 80 of about 83,354 (295)

Properties of Cement Mortar by Use of Hot-Melt Polyamides as Substitute for Fine Aggregate

open access: yesMaterials, 2015
This paper presents an experimental study on use of hot-melt polyamide (HMP) to prepare mortar specimens with improved crack healing and engineering properties.
Xiongzhou Yuan   +4 more
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Influence of limestone waste as partial replacement material for sand and marble powder in concrete properties

open access: yesHBRC Journal, 2012
Green concrete are generally composed of recycling materials as hundred or partial percent substitutes for aggregate, cement, and admixture in concrete. Limestone waste is obtained as a by-product during the production of aggregates through the crushing ...
Omar M. Omar   +3 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

RESISTIVITY AGAINST SULFATE ATTACK OF CONCRETEWITH HDPE AS PARTIAL SUBSTITUTE FOR FINE AGGREGATES

open access: yesInternational Journal of GEOMATE, 2021
High-Density Polyethylene (HDPE) when used as partial substitute of fine aggregates in concrete is investigated to determine if it addresses sulfate attack in concrete. Since HDPE is known to be resistant against chemical compounds including sodium sulfate, it is hypothesized in this study that sulfate attack problems in concrete will be lessened by ...
openaire   +1 more source

Mechanical Strength and Microstructure Properties of Concrete Incorporating Copper Slag as Fine Aggregate: A State-of-the-Art Review

open access: yesAdvance in Civil Engineering
Incorporation solid waste generated in industry into concrete production is considered an environmentally sustainable approach as it reduces pollution, lowers energy consumption, and mitigates the depletion of natural resources.
Tareg Abdalla Abdalla, T. S. Alahmari
semanticscholar   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Effects of bottom ash and granulated blast furnace slag as fine aggregate on abrasion resistance of concrete

open access: yesScience and Engineering of Composite Materials, 2017
Abrasion resistance is one of the most important durability properties of concrete. Especially, highway, airport and industrial floor pavements should be resistant to abrasion.
Bilir Turhan   +3 more
doaj   +1 more source

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