Results 131 to 140 of about 641 (161)

Comparative effects of fipronil and its metabolites sulfone and desulfinyl on the isolated rat liver mitochondria

Environmental Toxicology and Pharmacology, 2015
Fipronil is an insecticide extensively used to control pests in crops and animals. There are relates of poisoning due to exposure of fipronil in mammals and the liver has been suggested as potential target. In this study, we evaluated the effects of fipronil and its metabolites sulfone and desulfinyl on the bioenergetics, reactive oxygen species (ROS ...
Hyllana C D Medeiros, Fabio E Mingatto
exaly   +5 more sources

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Polypyrrole‐coated rubber foam sorbent for extraction of fipronil and fipronil sulfone in tea

Separation Science Plus, 2023
Abstract A polypyrrole‐coated rubber foam sorbent with a steel wire insert was developed for the magnetic solid phase extraction of fipronil and fipronil sulfone from tea samples for analysis by a gas chromatography‐electron capture detector.
Proespichaya Kanatharana, Chongdee Thammakhet   +1 more
exaly   +2 more sources

Analytical Method for Fipronil and Fipronil Sulfone in Livestock Products Using LC-MS/MS

Shokuhin Eiseigaku Zasshi Journal of the Food Hygienic Society of Japan, 2020
A rapid and sensitive method for the simultaneous determination of fipronil and fipronil sulfone (metabolite B) in livestock products was developed. The analytes were extracted from samples with acidic acetonitrile. The crude extracts were subjected to clean-up step using neutral alumina cartridge column.
Takatoshi Sakai, Satoru Nemoto
exaly   +3 more sources

Distribution of fipronil in humans, and adverse health outcomes of in utero fipronil sulfone exposure in newborns

International Journal of Hygiene and Environmental Health, 2019
Fipronil is a highly effective insecticide with extensive usages; however, its distribution and toxic/health effects in the human population after chronic exposure have not yet been clearly identified. Our objectives were to determine the levels of serum fipronil and fipronil sulfone, a primary fipronil metabolite, in a general and sensitive human ...
Young Ah Kim, Yeong Sook Yoon, Se Jeong Jeon   +2 more
exaly   +3 more sources

Toxicity and neurophysiological effects of fipronil and fipronil sulfone on the western corn rootworm (Coleoptera: Chrysomelidae)

Archives of Insect Biochemistry and Physiology, 1999
Fipronil is a member of the relatively new phenylpyrazole insecticide class that is active at the neuro-inhibitory gamma amino butyric acid (GABA)-gated chloride channel/ionopore complex. The toxicity and neurophysiological effects of fipronil and its oxidative sulfone metabolite [5-amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4 ...
Blair D Siegfried
exaly   +2 more sources

Quantification of fipronil and its metabolite fipronil sulfone in rat plasma over a wide range of concentrations by LC/UV/MS

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2010
Fipronil is an insecticide extensively used to treat pets, which has been identified as a potential thyroid disruptor in the rat. In this species, fipronil is mainly metabolized to fipronil sulfone and plasma concentrations of fipronil sulfone can be at least 20-fold higher than those of fipronil.
Marlene Z Lacroix, Pierre-Louis Toutain
exaly   +4 more sources

Utilization of common ditch vegetation in the reduction of fipronil and its sulfone metabolite

Pest Management Science, 2008
AbstractBACKGROUND: Fipronil, a phenylpyrazole insecticide, and its oxidative sulfone metabolite are two potential pollutants from treated rice and cotton production. A consequence of these pollutants occurring in surface runoff is degradation of downstream aquatic ecosystems. Utilization of primary intercept drainage ditches as management practices to
Robert Kröger
exaly   +3 more sources

Fipronil toxicity in northern bobwhite quail Colinus virginianus: Reduced feeding behaviour and sulfone metabolite formation

Chemosphere, 2011
Fipronil is a phenyl pyrazole insecticide registered for agricultural use in many countries. Avian exposure to fipronil occurs mainly by ingesting contaminated insects or seeds. There is little information regarding the toxicological effects of fipronil in avian species and even less research documenting avian behavioural responses to fipronil ...
William A Buttemer, Michael J Hooper, Lee B Astheimer   +2 more
exaly   +4 more sources

Behavior of nursery-box-applied fipronil and its sulfone metabolite in rice paddy fields

Agriculture, Ecosystems and Environment, 2013
Abstract The granular insecticide fipronil has been widely applied in rice nursery boxes, both before transplanting (BT) and during at-sowing (AS) treatments to control insect pests at the early stages of rice cultivation in Japan. Although a potential effect of fipronil on paddy ecosystems and downstream aquatic environments has been observed, the ...
Dang Quoc Thuyet, Hirozumi Watanabe, Takashi Motobayashi   +2 more
exaly   +2 more sources

Toxicity and Neurophysiological Effects of Fipronil and Its Oxidative Sulfone Metabolite on European Corn Borer Larvae (Lepidoptera: Crambidae)

Pesticide Biochemistry and Physiology, 2001
Abstract The phenylpyrazole insecticide fipronil is the first compound of its class to be registered for commercial use. The mode of action of this class of insecticides involves antagonism of the inhibitory neurotransmitter, γ-aminobutyric acid (GABA).
Blair D Siegfried
exaly   +2 more sources