Results 141 to 150 of about 641 (161)
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A Polyvinyl Alcohol Coated Copper Foam Solid Phase Extractor for Determining Fipronil and Fipronil Sulfone

ECS Transactions, 2022
Fipronil is a member of phenylpyrazole insecticide, which was widely used in agriculture to kill pests [1-2]. It can also form metabolite, such as fipronil sulfone by oxidation process, which is more toxic than parent compound [3-4]. Fipronil sulfone can persist for longer duration, which can easily bind to lipid-rich matrices and get into food chain ...
Sonam Choden   +3 more
openaire   +1 more source

Determination of Fipronil and Fipronil-Sulfone in Surface Waters of the Guandu River Basin by High-Performance Liquid Chromatography with Mass Spectrometry

Bulletin of Environmental Contamination and Toxicology, 2021
Fipronil (FIP) is a broad-spectrum insecticide used in the industrial, residential and agricultural sectors, which presents environmental and human health risks. Studies report its presence in aquatic environments in several countries, but in Brazil reports are scarce.
Thais P. Ferreira   +6 more
openaire   +2 more sources

A first approach using micellar electrokinetic capillary chromatography for the determination of fipronil and fipronil‐sulfone in eggs

ELECTROPHORESIS, 2019
AbstractFipronil is an insecticide that is not approved in the European Union in food. In 2017, fipronil was involved in a European health alert due to its presence in fresh hen eggs because of an illicit use in poultry farms, so reliable methods are needed to determine fipronil and its main metabolites in these matrixes.
M. Mar Aparicio‐Muriana   +3 more
openaire   +3 more sources

Biodegradation of fipronil and its metabolite fipronil sulfone by Streptomyces rochei strain AJAG7 and its use in bioremediation of contaminated soil

Pesticide Biochemistry and Physiology, 2019
Fipronil is a most widely used insecticide. It has been found to be highly toxic to insects with alarming decline in honey bees' population. It has shown to cause severe contamination of soil and water. The present study was undertaken to understand the degradation of fipronil and its metabolite fipronil sulfone using actinomycetes.
Jayanthi Abraham, Anudurga Gajendiran
openaire   +2 more sources

Rapid and Sensitive Quantitation of Fipronil and Its Metabolites Fipronil Sulfone, Fipronil Sulfide, and Fipronil Desulfinyl in Zebrafish Tissues by UHPLC‐MS/MS

Journal of Separation Science
ABSTRACT An ultra‐high performance liquid chromatography‐tandem mass spectrometry (UHPLC‐MS/MS) method was developed and validated for the simultaneous determination of fipronil and its three metabolites (fipronil sulfone, fipronil sulfide, and fipronil desulfinyl) in zebrafish tissues.
Meichen, Liu   +8 more
openaire   +2 more sources

Mechanisms for Selective Toxicity of Fipronil Insecticide and Its Sulfone Metabolite and Desulfinyl Photoproduct

Chemical Research in Toxicology, 1998
Fipronil, an N-phenylpyrazole with a trifluoromethylsulfinyl substituent, initiated the second generation of insecticides acting at the gamma-aminobutyric acid (GABA) receptor to block the chloride channel. The first generation includes the polychlorocycloalkanes alpha-endosulfan and lindane.
D, Hainzl, L M, Cole, J E, Casida
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Ecotoxicological impacts of fipronil sulfone: Developmental and behavioral disruptions in zebrafish embryos and larvae

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
Fipronil sulfone is a persistent oxidative metabolite of the insecticide fipronil, frequently detected in aquatic systems and known to exert neurotoxic effects on non-target organisms. Despite its environmental relevance, the developmental impacts of fipronil sulfone remain underexplored.
Bianca, de Arruda Leite   +4 more
openaire   +2 more sources

Sulfone Metabolite of Fipronil Blocks γ-Aminobutyric Acid- and Glutamate-Activated Chloride Channels in Mammalian and Insect Neurons

The Journal of Pharmacology and Experimental Therapeutics, 2005
Fipronil sulfone, a major metabolite of fipronil in both insects and mammals, binds strongly to GABA receptors and is thought to play a significant role in poisoning by fipronil. To better understand the mechanism of selective insecticidal action of fipronil, we examined the effects of its sulfone metabolite on GABA- and glutamate-activated chloride ...
Xilong, Zhao   +3 more
openaire   +2 more sources

Development of a Vortex-Assisted Dispersive Liquid-Liquid Microextraction (VA-DLLME) and LC-MS/MS Procedure for Simultaneous Determination of Fipronil and its Metabolite Fipronil Sulfone in Tomato Fruits

Food Analytical Methods, 2019
A rapid, simple, inexpensive, and reliable vortex-assisted dispersive liquid-liquid microextraction (VA-DLLME) method was developed for the determination of fipronil and its major metabolite, fipronil sulfone, in tomato fruits using liquid chromatography tandem mass spectrometry (LC-MS/MS). No salting-out or cleanup steps were required after extraction.
Osama I. Abdallah, Nevein S. Ahmed
openaire   +1 more source

Maternal exposure to fipronil results in sulfone metabolite enrichment and transgenerational toxicity in zebrafish offspring: Indication for an overlooked risk in maternal transfer?

Environmental Pollution, 2019
Ecotoxicological studies show the association between pesticide pollution and transgenerational toxicity in aquatic organisms. However, a less considered risk is that many pesticides can be metabolized and transferred to offspring as new toxicants. In this study, we used zebrafish to evaluate the maternal transfer risk of fipronil (FIP), which is a ...
Chao Xu   +6 more
openaire   +2 more sources

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