Results 141 to 150 of about 1,110 (181)
Some of the next articles are maybe not open access.
Archives of Insect Biochemistry and Physiology, 1999
Fipronil is a member of the relatively new phenylpyrazole insecticide class that is active at the neuro-inhibitory gamma amino butyric acid (GABA)-gated chloride channel/ionopore complex. The toxicity and neurophysiological effects of fipronil and its oxidative sulfone metabolite [5-amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4 ...
Michael E. Scharf, Blair D. Siegfried
openaire +1 more source
Fipronil is a member of the relatively new phenylpyrazole insecticide class that is active at the neuro-inhibitory gamma amino butyric acid (GABA)-gated chloride channel/ionopore complex. The toxicity and neurophysiological effects of fipronil and its oxidative sulfone metabolite [5-amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4 ...
Michael E. Scharf, Blair D. Siegfried
openaire +1 more source
Pesticide Biochemistry and Physiology, 2019
Fipronil is a most widely used insecticide. It has been found to be highly toxic to insects with alarming decline in honey bees' population. It has shown to cause severe contamination of soil and water. The present study was undertaken to understand the degradation of fipronil and its metabolite fipronil sulfone using actinomycetes.
Jayanthi Abraham, Anudurga Gajendiran
openaire +2 more sources
Fipronil is a most widely used insecticide. It has been found to be highly toxic to insects with alarming decline in honey bees' population. It has shown to cause severe contamination of soil and water. The present study was undertaken to understand the degradation of fipronil and its metabolite fipronil sulfone using actinomycetes.
Jayanthi Abraham, Anudurga Gajendiran
openaire +2 more sources
Journal of Chromatography B, 2010
Fipronil is an insecticide extensively used to treat pets, which has been identified as a potential thyroid disruptor in the rat. In this species, fipronil is mainly metabolized to fipronil sulfone and plasma concentrations of fipronil sulfone can be at least 20-fold higher than those of fipronil.
Lacroix, Marlène Z. +3 more
openaire +3 more sources
Fipronil is an insecticide extensively used to treat pets, which has been identified as a potential thyroid disruptor in the rat. In this species, fipronil is mainly metabolized to fipronil sulfone and plasma concentrations of fipronil sulfone can be at least 20-fold higher than those of fipronil.
Lacroix, Marlène Z. +3 more
openaire +3 more sources
Chemical Research in Toxicology, 1998
Fipronil, an N-phenylpyrazole with a trifluoromethylsulfinyl substituent, initiated the second generation of insecticides acting at the gamma-aminobutyric acid (GABA) receptor to block the chloride channel. The first generation includes the polychlorocycloalkanes alpha-endosulfan and lindane.
D, Hainzl, L M, Cole, J E, Casida
openaire +2 more sources
Fipronil, an N-phenylpyrazole with a trifluoromethylsulfinyl substituent, initiated the second generation of insecticides acting at the gamma-aminobutyric acid (GABA) receptor to block the chloride channel. The first generation includes the polychlorocycloalkanes alpha-endosulfan and lindane.
D, Hainzl, L M, Cole, J E, Casida
openaire +2 more sources
Utilization of common ditch vegetation in the reduction of fipronil and its sulfone metabolite
Pest Management Science, 2008AbstractBACKGROUND: Fipronil, a phenylpyrazole insecticide, and its oxidative sulfone metabolite are two potential pollutants from treated rice and cotton production. A consequence of these pollutants occurring in surface runoff is degradation of downstream aquatic ecosystems. Utilization of primary intercept drainage ditches as management practices to
Robert, Kröger, Matt T, Moore
openaire +2 more sources
Journal of Separation Science
ABSTRACT An ultra‐high performance liquid chromatography‐tandem mass spectrometry (UHPLC‐MS/MS) method was developed and validated for the simultaneous determination of fipronil and its three metabolites (fipronil sulfone, fipronil sulfide, and fipronil desulfinyl) in zebrafish tissues.
Meichen Liu +8 more
openaire +1 more source
ABSTRACT An ultra‐high performance liquid chromatography‐tandem mass spectrometry (UHPLC‐MS/MS) method was developed and validated for the simultaneous determination of fipronil and its three metabolites (fipronil sulfone, fipronil sulfide, and fipronil desulfinyl) in zebrafish tissues.
Meichen Liu +8 more
openaire +1 more source
Chemosphere, 2011
Fipronil is a phenyl pyrazole insecticide registered for agricultural use in many countries. Avian exposure to fipronil occurs mainly by ingesting contaminated insects or seeds. There is little information regarding the toxicological effects of fipronil in avian species and even less research documenting avian behavioural responses to fipronil ...
Kitulagodage, Malsha +4 more
openaire +3 more sources
Fipronil is a phenyl pyrazole insecticide registered for agricultural use in many countries. Avian exposure to fipronil occurs mainly by ingesting contaminated insects or seeds. There is little information regarding the toxicological effects of fipronil in avian species and even less research documenting avian behavioural responses to fipronil ...
Kitulagodage, Malsha +4 more
openaire +3 more sources
Behavior of nursery-box-applied fipronil and its sulfone metabolite in rice paddy fields
Agriculture, Ecosystems & Environment, 2013Abstract The granular insecticide fipronil has been widely applied in rice nursery boxes, both before transplanting (BT) and during at-sowing (AS) treatments to control insect pests at the early stages of rice cultivation in Japan. Although a potential effect of fipronil on paddy ecosystems and downstream aquatic environments has been observed, the ...
Dang Quoc Thuyet +3 more
openaire +1 more source
Environmental Toxicology and Pharmacology, 2015
Fipronil is an insecticide extensively used to control pests in crops and animals. There are relates of poisoning due to exposure of fipronil in mammals and the liver has been suggested as potential target. In this study, we evaluated the effects of fipronil and its metabolites sulfone and desulfinyl on the bioenergetics, reactive oxygen species (ROS ...
Tavares, Marco A. +5 more
openaire +3 more sources
Fipronil is an insecticide extensively used to control pests in crops and animals. There are relates of poisoning due to exposure of fipronil in mammals and the liver has been suggested as potential target. In this study, we evaluated the effects of fipronil and its metabolites sulfone and desulfinyl on the bioenergetics, reactive oxygen species (ROS ...
Tavares, Marco A. +5 more
openaire +3 more sources
The Journal of Pharmacology and Experimental Therapeutics, 2005
Fipronil sulfone, a major metabolite of fipronil in both insects and mammals, binds strongly to GABA receptors and is thought to play a significant role in poisoning by fipronil. To better understand the mechanism of selective insecticidal action of fipronil, we examined the effects of its sulfone metabolite on GABA- and glutamate-activated chloride ...
Xilong, Zhao +3 more
openaire +2 more sources
Fipronil sulfone, a major metabolite of fipronil in both insects and mammals, binds strongly to GABA receptors and is thought to play a significant role in poisoning by fipronil. To better understand the mechanism of selective insecticidal action of fipronil, we examined the effects of its sulfone metabolite on GABA- and glutamate-activated chloride ...
Xilong, Zhao +3 more
openaire +2 more sources