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Disease outcome and cytokine responses in cats immunized with an avirulent feline infectious peritonitis virus (FIPV)-UCD1 and challenge-exposed with virulent FIPV-UCD8 [PDF]
Journal of Feline Medicine and Surgery, 2004 Eight cats were immunized with an avirulent strain of feline infectious peritonitis virus (FIPV)-UCD1, then challenge-exposed to a highly virulent cat passaged strain (FIPV-UCD8). Th1 and Th2 cytokine profiles in the peripheral blood mononuclear cells (PBMCs) were measured throughout in the experiment.
, N C Pedersen
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Type IV Hypersensitivity in the Pathogenesis of FIPV‐Induced Lesions
Journal of Veterinary Medicine, Series B, 1998SummaryIn focal lesions of feline infectious peritonitis (FIP), the cells involved in the delayed‐type hypersensitivity were identified in formalin‐fixed paraffin‐embedded and frozen samples taken from 35 affected cats. The clinical diagnosis of FIP was confirmed by necropsy, histology and direct immunofluorescence against the coronaviruses on ...
S. Paltrinieri +3 more
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Vaccine, 1990 Cats vaccinated intranasally (i.n.) with a temperature sensitive feline infectious peritonitis virus (ts-FIPV) vaccine were protected against an FIP-inducing challenge. Seventeen of 20 vaccinated cats (85%) survived a rigorous virulent FIPV challenge that caused FIP in 12 of 12 non-vaccinated cats (100%), 10 (83%) of which died.
Gerber, J.D. +8 more
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Porcine epidemic diarrhea virus (CV 777) and feline infectious peritonitis virus (FIPV) are antigenically related [PDF]
Archives of Virology, 1988 Using gut sections from pigs infected with porcine epidemic diarrhea virus (strain CV 777) and ascitic fluid from cats which had succumbed to feline infectious peritonitis (FIP), a weak cross reaction was found by immunofluorescence. Its specificity was confirmed when detergent-treated purified CV 777 showed a prominent reaction with FIPV antibodies in
Marian C Horzinek, M Pensaert
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Strategies for combating FIPV infection: antiviral agents and vaccines
Research in Veterinary ScienceFeline infectious peritonitis virus (FIPV) is a deadly virus that causes feline infectious peritonitis (FIP) in cats. FIP is a biotype of feline coronavirus (FCoV). Currently, the prevention and treatment of FIPV is challenged by the absence of adequate clinical treatment drugs and vaccines that offer strong immune protection complicated.
Fan, Gao, Guilan, Wen
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Veterinary Microbiology, 2007 Feline infectious peritonitis virus (FIPV) positive cells are present in pyogranulomas and exudates from cats with FIP. These cells belong mainly to the monocyte/macrophage lineage. How these cells survive in immune cats is not known. In this study, FIPV positive cells were isolated from pyogranulomas and exudates of 12 naturally FIPV-infected cats and
H J Nauwynck
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Archives of Virology
Feline coronavirus (FCoV) has two biotypes: feline enteric coronavirus (FECV), which typically causes mild intestinal infections, and feline infectious peritonitis virus (FIPV), a virulent form associated with a fatal systemic and infectious disease in cats, known as feline infectious peritonitis (FIP).
Lai Thi Lan Huong +2 more
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Feline coronavirus (FCoV) has two biotypes: feline enteric coronavirus (FECV), which typically causes mild intestinal infections, and feline infectious peritonitis virus (FIPV), a virulent form associated with a fatal systemic and infectious disease in cats, known as feline infectious peritonitis (FIP).
Lai Thi Lan Huong +2 more
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Antibody-based Therapeutic Drug Development of Feline Infectious Peritonitis (FIPV) 2866
The Journal of ImmunologyAbstract Description Feline infectious peritonitis (FIP) is a fatal progressive viral disease, and no effective therapy and safe vaccine are available due to antibody-dependent enhancement (ADE).
Yi Wen Shen, Yen Chen Chang
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Veterinary Microbiology
Feline infectious peritonitis (FIP) is a fatal disease caused by a mutant strain of feline coronavirus (FCoV), and its progression is closely related to gut microbiota and immune response. This study aimed to investigate the changes in the fecal microbiota composition of cats experimentally infected with FIPV, with and without antiviral treatment ...
Guiqing Peng, Yuejun Shi
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Feline infectious peritonitis (FIP) is a fatal disease caused by a mutant strain of feline coronavirus (FCoV), and its progression is closely related to gut microbiota and immune response. This study aimed to investigate the changes in the fecal microbiota composition of cats experimentally infected with FIPV, with and without antiviral treatment ...
Guiqing Peng, Yuejun Shi
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International Journal of Pharmaceutics
The enhancement of conventional liposome and lipid nanoparticle (LNP) methodologies in the formulation and deployment of messenger RNA (mRNA) vaccines necessitates further refinement to augment both their effectiveness and biosafety profiles. Additionally, researching these innovative delivery carrier materials represents both a prominent focus and a ...
Na, Lu +12 more
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The enhancement of conventional liposome and lipid nanoparticle (LNP) methodologies in the formulation and deployment of messenger RNA (mRNA) vaccines necessitates further refinement to augment both their effectiveness and biosafety profiles. Additionally, researching these innovative delivery carrier materials represents both a prominent focus and a ...
Na, Lu +12 more
openaire +2 more sources