Results 101 to 110 of about 3,798 (191)

Identification of Potential Inhibitors of the SARS‐CoV‐2 NSP13 Helicase via Structure‐Based Ligand Design, Molecular Docking and Nonequilibrium Alchemical Simulations

open access: yesChemMedChem, Volume 19, Issue 10, May 17, 2024.
The channel for RNA unwinding of NSP13 SARS‐CoV‐2 helicase is highly conserved in alpha and beta mammals coronavirus. Exploiting a funnel‐like computational pipeline, we identified several micromolar or submicromolar NSP13 ligands blocking the central channel of NSP13.
Giorgio Di Paco   +2 more
wiley   +1 more source

A highly conserved WDYPKCDRA epitope in the RNA directed RNA polymerase of human coronaviruses can be used as epitope-based universal vaccine design [PDF]

open access: yes, 2014
BACKGROUND: Coronaviruses are the diverse group of RNA virus. From 1960, six strains of human coronaviruses have emerged that includes SARS-CoV and the recent infection by deadly MERS-CoV which is now going to cause another outbreak.
Abul Bashar Mir Md Islam, Refat Sharmin
core   +1 more source

Estado actual de la vacunación frente a las enfermedades infecciosas del gato [PDF]

open access: yes, 1999
Los nuevos conocimientos sobre vacunación, la existencia de nuevos productos inmunizantes para el gato, el mejor conocimiento de los efectos no deseados derivados de la aplicación de vacunas y las nuevas tecnologías aplicadas a la producción de vacunas ...
Simón Valencia, María Carmen
core  

The nucleotide sequence of the peplomer gene of porcine transmissible gastroenteritis virus (TGEV): comparison with the sequence of the peplomer protein of feline infectious peritonitis virus (FIPV)

open access: yesVirus Research, 1987
The amino acid sequence of the peplomer protein of transmissible gastroenteritis virus (TGEV) has been derived from the cloned cDNA sequence. The gene encodes a protein of 1447 amino acids with a molecular weight of 159 574. Comparison with the primary structure of the peplomer protein of feline infectious peritonitis virus (FIPV) (de Groot et al ...
Horzinek, M.C.   +4 more
openaire   +3 more sources

Dengue Hemorrhagic Fever in Infants: Research Opportunities Ignored

open access: yesEmerging Infectious Diseases, 2002
The age distribution of cases of dengue hemorrhagic fever and dengue shock syndrome (DHF/DSS) in infants under the age of 1 year are reported from Bangkok, Thailand, and for the first time for Ho Chi Minh City, Vietnam; Yangon, Myanmar; and Surabaya ...
Scott B. Halstead   +9 more
doaj   +1 more source

Predictors of oropharyngeal cancer survival in Europe [PDF]

open access: yes, 2018
Objectives: HPV16-positive oropharyngeal cancer (OPC) patients experience better outcomes compared to HPV16-negative patients. Currently, strategies for treatment de-escalation are based on HPV status, smoking history and disease stage.
Abedi-Ardekani, B.   +26 more
core   +4 more sources

Current status on treatment options for feline infectious peritonitis and SARS-CoV-2 positive cats

open access: yesVeterinary Quarterly, 2020
Feline infectious peritonitis (FIP) is a viral-induced, immune-mediated disease of cats caused by virulent biotypes of feline coronaviruses (FCoV), known as the feline infectious peritonitis virus (FIPV).
Aaron M. Izes   +3 more
doaj   +1 more source

3D Maxwell's equations and orthogonal nonconforming meshes: a hp-type Discontinuous Galerkin method [PDF]

open access: yes, 2003
We present a Discontinuous Galerkin scheme to solve the time-domain Maxwell's equations on conforming or nonconforming orthogonal grids. The method relies on a set of local basis functions whose degree may vary at subgrid interfaces.
Canouet, Nicolas   +2 more
core   +2 more sources

Serological survey of catteries for cats infected with feline coronavirus [PDF]

open access: yes, 2005
A serological survey on antibodies against feline coronavirus (FCo V) was conducted in four catteries in Klang Valley, Selangor, Malaysia. A total number of 24 cats of various breeds, ages and gender were randomly sampled from each cattery.
A. W., Siti Farawahida   +5 more
core  

Spike Protein Fusion Peptide and Feline Coronavirus Virulence

open access: yesEmerging Infectious Diseases, 2012
Coronaviruses are well known for their potential to change their host or tissue tropism, resulting in unpredictable new diseases and changes in pathogenicity; severe acute respiratory syndrome and feline coronaviruses, respectively, are the most ...
Hui-Wen Chang   +4 more
doaj   +1 more source

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