Results 81 to 90 of about 3,798 (191)

Feline Infectious Peritonitis Virus Nsp5 Inhibits Type I Interferon Production by Cleaving NEMO at Multiple Sites

Viruses, 2019
Feline infectious peritonitis (FIP), caused by virulent feline coronavirus, is the leading infectious cause of death in cats. The type I interferon (type I IFN)-mediated immune responses provide host protection from infectious diseases.
Si Chen, Jin Tian, Zhijie Li, Hongtao Kang, Jikai Zhang, Jiapei Huang, Hang Yin, Xiaoliang Hu, Liandong Qu   +8 more
doaj   +1 more source

Repurposing old drugs as antiviral agents for coronaviruses

Biomedical Journal, 2020
Background: New therapeutic options to address the ongoing coronavirus disease 2019 (COVID-19) pandemic are urgently needed. One possible strategy is the repurposing of existing drugs approved for other indications as antiviral agents for severe acute ...
Cheng-Wei Yang, Tzu-Ting Peng, Hsing-Yu Hsu, Yue-Zhi Lee, Szu-Huei Wu, Wen-Hsing Lin, Yi-Yu Ke, Tsu-An Hsu, Teng-Kuang Yeh, Wen-Zheng Huang, Jiunn-Horng Lin, Huey-Kang Sytwu, Chiung-Tong Chen, Shiow-Ju Lee   +13 more
doaj   +1 more source

Development of monoclonal antibodies (MAbs) to feline interferon (fIFN)- γ as tools to evaluate cellular immune responses to feline infectious peritonitis virus (FIPV) [PDF]

Journal of Feline Medicine and Surgery, 2011
Feline infectious peritonitis virus (FIPV) can cause a lethal disease in cats, feline infectious peritonitis (FIP). The antibody-dependent enhancement (ADE) of FIPV infection has been recognised in experimentally infected cats, and cellular immunity is considered to play an important role in preventing the onset of FIP. To evaluate
Satoh, Ryoichi, Kaku, Ayumi, Satomura, Megumi, Kohori, Michiyo, Noura, Kanako, Furukawa, Tomoko, Kotake, Masako, Takano, Tomomi, Hohdatsu, Tsutomu   +8 more
openaire   +2 more sources

Predictive factors associated with short‐term mortality in cats with feline infectious peritonitis treated with remdesivir or GS‐441524 or both

Journal of Veterinary Internal Medicine, Volume 39, Issue 1, January/February 2025.
Abstract Background Although most cats with feline infectious peritonitis (FIP) respond to treatment with remdesivir or GS‐441524 or both with uneventful clinical courses, some die despite treatment. Objective Identify predictive factors associated with short‐term mortality in cats with FIP treated with IV remdesivir or PO GS‐441524 or both.
Sho Goto, Tsuyoshi Kamiyoshi, Ryota Iwasaki   +2 more
wiley   +1 more source

Long-Term Maraviroc Use As Salvage Therapy in HIV-2 Infection [PDF]

, 2012
publishersversionpublishe
Caixas, U, Faustino, I, Ferreira, J, Germano, I, Grilo, N, Lampreia, F, Marinho, A, Monteiro, E, Pereira, S   +8 more
core   +1 more source

Circulation and Genetic Characterizations of Coronaviruses From Companion Animals in Chengdu, Southwest China: One‐Year Postpandemic

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Coronaviruses (CoVs) can cross species barriers and endanger public health. Despite reports on their circulation and evolution in companion animals during the pandemic, postpandemic surveillance remains crucial. Therefore, during the first postpandemic year, 309 samples from 263 companion animals (cats and dogs) in Chengdu, China, were detected for ...
Linxuan Liao, Shanshan Wu, Yihang Xu, Mengxi Cao, Xiao Zhang, Liying Yi, Baochao Zhang, Jiayi Chen, Xin Xu, Xiaofang Pei, Francesco Mira   +10 more
wiley   +1 more source

Emergence of Canine Parvovirus Type 2a and Canine Enteric Coronavirus in Diarrheal Outbreaks Among Farmed Raccoon Dogs in China

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Canine parvovirus (CPV) and canine enteric coronavirus (CCoV) are primary viral pathogens responsible for causing diarrhea in carnivores. CCoV infection generally induces mild enteritis, whereas infections solely by CPV or coinfections involving both CPV and CCoV frequently result in severe diarrhea and can lead to fatal outcomes in affected animals ...
Rongguang Lu, Haixu Cao, Wei Yang, Jianhai Fu, Tingli Qian, Chengqi Zhang, Na Feng, Bo Hu, Liwen Xu, Shuangshuang Li, Guanyu Zhao, Qiumei Shi, Deyue Zang, Guobao Li, Xue Bai, Nan-Hua Chen   +15 more
wiley   +1 more source

An octavalent dendrimer of multiple antigenic peptide with a property of pan-coronavirus IgM induction improved clinical signs of feline infectious peritonitis in cats

Veterinary Vaccine
Feline infectious peritonitis (FIP) is a lethal disease caused by a pathogenic coronavirus, feline infectious peritonitis virus (FIPV), in cats. Effective vaccines have been unsuccessful due to the frequent mutation of FIPV and antibody-dependent ...
Takuya Nara, Hiroshi Shimoda, Chitose Suzuki, Ngo Thuy Bao Tran, Hina Tsukada, Hiroki Okayama, Hu Weiyin, Miho Obata, Saki Mitsunaga, Masashi Sakurai, Yudai Kuroda, Ken Maeda, Masato Kubo, Takashi Saito, Kenichi Masuda   +14 more
doaj   +1 more source

Energy and economic performance of rooftop PV panels in the hot and dry climate of Iran [PDF]

, 2018
Photovoltaic (PV) Panels, one of the more promising renewable energy technologies, are growing rapidly nowadays, especially in developed countries. However, these systems have not achieved public acceptance in some countries due to low energy efficiency ...
Korsavi, Sepideh Sadat, Tahsildoost, Mohammad, Zomorodian, Zahra Sadat   +2 more
core   +2 more sources

Susceptibility of Ferret and Cat to Porcine Deltacoronavirus: Evidence of Infection in Ferrets But Not Cats

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Coronaviruses (CoVs) cause gastrointestinal and respiratory disorders and have a wide host range. Porcine deltacoronavirus (PDCoV) is an enteropathogenic CoV and a member of the Deltacoronavirus (δ‐CoV) genus and was discovered in 2012. With a high fatality rate, PDCoV is primarily responsible for severe diarrhea in pigs, especially in newborn piglets,
Shuhuai Meng, Renqiang Liu, Hao Zhang, Guangli Hu, Lei Shuai, Huijuan Guo, Yijing Dang, Yongchang Cao, Zhigao Bu, Zhiyuan Wen, Nan-Hua Chen   +10 more
wiley   +1 more source