Results 71 to 80 of about 2,257 (148)

An octavalent dendrimer of multiple antigenic peptide with a property of pan-coronavirus IgM induction improved clinical signs of feline infectious peritonitis in cats

Veterinary Vaccine
Feline infectious peritonitis (FIP) is a lethal disease caused by a pathogenic coronavirus, feline infectious peritonitis virus (FIPV), in cats. Effective vaccines have been unsuccessful due to the frequent mutation of FIPV and antibody-dependent ...
Takuya Nara, Hiroshi Shimoda, Chitose Suzuki, Ngo Thuy Bao Tran, Hina Tsukada, Hiroki Okayama, Hu Weiyin, Miho Obata, Saki Mitsunaga, Masashi Sakurai, Yudai Kuroda, Ken Maeda, Masato Kubo, Takashi Saito, Kenichi Masuda   +14 more
doaj   +1 more source

Comparative in vivo analysis of recombinant type II feline coronaviruses with truncated and completed ORF3 region.

PLoS ONE, 2014
Our previous in vitro comparative study on a feline coronavirus (FCoV) pair, differing only in the intactness of their ORF3abc regions, showed that the truncated ORF3abc plays an important role in the efficient macrophage/monocyte tropism of type II ...
Ádám Bálint, Attila Farsang, Zoltán Zádori, Sándor Belák   +3 more
doaj   +1 more source

Emergence of Canine Parvovirus Type 2a and Canine Enteric Coronavirus in Diarrheal Outbreaks Among Farmed Raccoon Dogs in China

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Canine parvovirus (CPV) and canine enteric coronavirus (CCoV) are primary viral pathogens responsible for causing diarrhea in carnivores. CCoV infection generally induces mild enteritis, whereas infections solely by CPV or coinfections involving both CPV and CCoV frequently result in severe diarrhea and can lead to fatal outcomes in affected animals ...
Rongguang Lu, Haixu Cao, Wei Yang, Jianhai Fu, Tingli Qian, Chengqi Zhang, Na Feng, Bo Hu, Liwen Xu, Shuangshuang Li, Guanyu Zhao, Qiumei Shi, Deyue Zang, Guobao Li, Xue Bai, Nan-Hua Chen   +15 more
wiley   +1 more source

Susceptibility of Ferret and Cat to Porcine Deltacoronavirus: Evidence of Infection in Ferrets But Not Cats

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Coronaviruses (CoVs) cause gastrointestinal and respiratory disorders and have a wide host range. Porcine deltacoronavirus (PDCoV) is an enteropathogenic CoV and a member of the Deltacoronavirus (δ‐CoV) genus and was discovered in 2012. With a high fatality rate, PDCoV is primarily responsible for severe diarrhea in pigs, especially in newborn piglets,
Shuhuai Meng, Renqiang Liu, Hao Zhang, Guangli Hu, Lei Shuai, Huijuan Guo, Yijing Dang, Yongchang Cao, Zhigao Bu, Zhiyuan Wen, Nan-Hua Chen   +10 more
wiley   +1 more source

Sensitivity and specificity of a real-time reverse transcriptase polymerase chain reaction detecting feline coronavirus mutations in effusion and serum/plasma of cats to diagnose feline infectious peritonitis

BMC Veterinary Research, 2017
Background Feline coronavirus (FCoV) exists as two pathotypes, and FCoV spike gene mutations are considered responsible for the pathotypic switch in feline infectious peritonitis (FIP) pathogenesis.
Sandra Felten, Christian M. Leutenegger, Hans-Joerg Balzer, Nikola Pantchev, Kaspar Matiasek, Gerhard Wess, Herman Egberink, Katrin Hartmann   +7 more
doaj   +1 more source

Development and Application of an Indirect Enzyme‐Linked Immunosorbent Assay Based on a Recombinant Matrix Protein for the Serological Study of Porcine Deltacoronavirus in Mexican Pigs

Veterinary Medicine and Science, Volume 10, Issue 6, November 2024.
Developed an iELISA with the PDCoV recombinant protein M to sero‐evaluate 516 samples from 4 different states of Mexico and serologically compare PDCoV/PEDV. ABSTRACT Porcine deltacoronavirus (PDCoV) is an infectious disease that causes diarrhoea in pigs of different ages; however, piglets are more susceptible. PDCoV was first reported in 2012 in China
Francisco Jesus Castañeda Montes, José Luis Cerriteño Sánchez, Julieta Sandra Cuevas‐Romero, María Azucena Castañeda Montes, Susana Mendoza Elvira   +4 more
wiley   +1 more source

Open label clinical trial of orally administered molnupiravir as a first‐line treatment for naturally occurring effusive feline infectious peritonitis

Journal of Veterinary Internal Medicine, Volume 38, Issue 6, Page 3087-3094, November/December 2024.
Abstract Background Before the discovery of effective antiviral drugs, feline infectious peritonitis (FIP) was a uniformly fatal disease of cats. Multiple antiviral treatments have been recognized, but optimization of treatment protocols is needed. Objective To evaluate the efficacy of PO molnupiravir (MPV; EIDD‐2801) to treat effusive FIP. Animals Ten
Krystle L. Reagan, Terza Brostoff, Jully Pires, Amy Rose, Diego Castillo, Brian G. Murphy   +5 more
wiley   +1 more source

Broad‐Spectrum Antiviral Activity of the Orally Bioavailable Antiviral ATV014 Against Multiple Coronaviruses

MedComm, Volume 6, Issue 5, May 2025.
Sidi Yang, Kun Li, Qifan Zhou, Xumu Zhang, Deyin Guo   +4 more
wiley   +1 more source

Dengue Hemorrhagic Fever in Infants: Research Opportunities Ignored

Emerging Infectious Diseases, 2002
The age distribution of cases of dengue hemorrhagic fever and dengue shock syndrome (DHF/DSS) in infants under the age of 1 year are reported from Bangkok, Thailand, and for the first time for Ho Chi Minh City, Vietnam; Yangon, Myanmar; and Surabaya ...
Scott B. Halstead, Nguyen Trong Lan, Thein Thein Myint, Than Nu Shwe, Ananda Nisalak, Siripen Kalyanarooj, Suchitra Nimmannitya, Soegeng Soegijanto, David W. Vaughn, Timothy P. Endy   +9 more
doaj   +1 more source

Spike Protein Fusion Peptide and Feline Coronavirus Virulence

Emerging Infectious Diseases, 2012
Coronaviruses are well known for their potential to change their host or tissue tropism, resulting in unpredictable new diseases and changes in pathogenicity; severe acute respiratory syndrome and feline coronaviruses, respectively, are the most ...
Hui-Wen Chang, Herman F. Egberink, Rebecca Halpin, David J. Spiro, Peter J.M. Rottier   +4 more
doaj   +1 more source