Results 141 to 150 of about 21,179 (270)

Interleukin‐10 Derived Apoptotic Vesicles Enhance Scarless Skin Healing by Modulating Fibroblast Metabolism and Fibrosis Pathways

Cell Proliferation, Volume 59, Issue 5, May 2026.
IL10_ApoEVs, generated during IL‐10‐induced fibroblast apoptosis, reprogram fibroblast metabolism and inhibit fibrosis to promote scarless skin healing. By enhancing mitochondrial OXPHOS, suppressing glycolysis, and downregulating Hedgehog signaling, IL10_ApoEVs shift collagen deposition toward regenerative type III collagen, offering a novel strategy ...
Yang Zou, Jinglun Zhang, Wenxuan Mao, Shuting Jiang, Cheng Xu, Jiayi Meng, Heng Dong, Yongbin Mou   +7 more
wiley   +1 more source

Application of luciferase assay for ATP to antimicrobial drug susceptibility [PDF]

, 1977
The susceptibility of bacteria, particularly those derived from body fluids, to antimicrobial agents is determined in terms of an ATP index measured by culturing a bacterium in a growth medium.
Barza, M. J., Chappelle, E. W., Picciolo, G. L., Tuttle, S. A., Vellend, H., Weinstein, L.   +5 more
core   +1 more source

Tandem MADS‐Box Genes FUL2 and MADS1 Form a Regulatory Module to Repress Serotonin Biosynthesis via Direct ASMT5 Activation in Tomato Fruit

Plant Biotechnology Journal, Volume 24, Issue 5, Page 2891-2902, May 2026.
ABSTRACT The regulation of serotonin metabolism during fruit development and ripening remains poorly understood, despite its potential roles in plant defence and human nutrition. Here, we demonstrated that the MADS‐box transcription factor FUL2 acts as a key repressor of serotonin accumulation in tomato by forming a functional module with MADS1. CRISPR‐
Yaping Xu, Huimin Jia, Dengguo Tang, Lijun Zhang, Xinqin Liu, Junjie Rong, Yunai Lv, Zhaobo Lang, Qingfeng Niu   +8 more
wiley   +1 more source

Near-infrared in vivo imaging system for dynamic visualization of lung-colonizing bacteria in mouse pneumonia

Microbiology Spectrum
In vivo imaging of bacterial infection models enables noninvasive and temporal analysis of individuals, enhancing our understanding of infectious disease pathogenesis.
Daiki Yamaguchi, Go Kamoshida, Syun Kawakubo, Saki Azuma, Takamitsu Tsuji, Nobuo Kitada, Ryohei Saito-Moriya, Noriteru Yamada, Rentaro Tanaka, Ayane Okuda, Keisuke Ueyama, Shingo Isaka, Manaha Tomita, Ryuichi Nakano, Yuji Morita, Hisakazu Yano, Shojiro A. Maki, Kinnosuke Yahiro, Shinichi Kato   +18 more
doaj   +1 more source

Adenosine 5'-triphosphate sulphurylase from rice shoots: partial purification and properties [PDF]

, 1980
ATP-sulphurplase was found in the soluble fraction of cell extracts ofrice shoots. The enzyme was purified 44-fold by ammonium sulphate fractionation, DEAE-cellulose and sephadex G-200 chrmatography.
Kooi, E. T., Mohamad, Aminuddin
core  

Transmembrane Protein GbTMEM209 Inhibits Fibre Elongation via Competitive Interaction With GbHOX3 in Gossypium barbadense

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3087-3105, May 2026.
ABSTRACT Sea Island cotton (Gossypium barbadense) produces premium‐quality fibres, yet the genetic basis underlying its fibre development remains elusive. Here, we identify two key non‐synonymous single nucleotide polymorphisms (SNPs, G/C and G/A) in the gene Gbar_D13G024080, which encodes the TRANSMEMBRANE PROTEIN 209 (TMEM209). These SNPs resulted in
Kaiyun Jiang, Nan Zhao, Jie Kong, Anhui Guo, Yuqi Liu, Meng Wang, Zixin Zhou, Mengling Sun, Weiran Wang, Jiahui Zhu, Daojun Yuan, Zhuanxia Pan, Pengbo Li, Suen Liu, Baosheng Guo, Huijing Li, Jingrou Zhang, Bin Li, Zhanghao Xia, Beibei Lv, Junyi Geng, Baoliang Wang, Alifu Aierxi, Xianlong Zhang, Lili Tu, Jinping Hua   +25 more
wiley   +1 more source

Genetic analysis of the human tumor necrosis factor alpha/cachectin promoter region in a macrophage cell line. [PDF]

, 1989
The 615-bp 5' flanking region of the human TNF-alpha/cachectin gene was isolated and ligated to the luciferase reporter gene. In addition, a series of truncated promoter constructs was generated by exonuclease III digestion.
Economou, JS, Essner, R, Gasson, JC, McBride, WH, Morton, DL, Rhoades, K   +5 more
core  

Cloning, Sequencing, and Characterization of Luciola italica Luciferase [PDF]

, 2006
The characteristic yellow-green light of a firefly is the result of a multi-step reaction catalyzed by the luciferase enzyme. This enzyme has many applications in the biomedical field and ongoing work is being done to alter its properties to better fit ...
DeAngelis, Jennifer P.
core   +1 more source

BPM31510 Increases the CoQ Pool in Chemically Induced CoQ‐Deficient Cells, CoQ‐Deficient Patient Fibroblasts, and in Metabolically Active Murine Tissues

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Graphical abstract illustrating the in vitro and in vivo experimental workflow used to compare BPM31510, a nanoliposomal formulation of oxidized CoQ10, with conventional CoQ10. Chemically induced CoQ‐deficient SH‐SY5Y cells, CoQ‐deficient patient fibroblasts, and C57BL/6J mice receiving oral CoQ10 or intraperitoneal BPM31510 were subjected to plasma ...
Juan J. Aristizabal‐Henao, Sarah R. Wessel, Sylwia A. Stopka, Srada Karmacharya, Devon Van Cura, Alba Pesini, Kelsey R. Nickerson, Kashni Grover, Oksana Zavidij, Archna Ravi, Andressa L. Mota, Kenneth M. Rosen, Maria‐Dorothea Nastke, Megan K. Cox, Niven R. Narain, Vijay Modur, Catarina M. Quinzii, Stephane Gesta, Michael A. Kiebish   +18 more
wiley   +1 more source

Sustained delivery and molecular targeting of a therapeutic monoclonal antibody to metastases in the central nervous system of mice. [PDF]

, 2019
Approximately 15-40% of all cancers develop metastases in the central nervous system (CNS), yet few therapeutic options exist to treat them. Cancer therapies based on monoclonal antibodies are widely successful, yet have limited efficacy against CNS ...
Chen, Irvin SY, Guan, Xin, Kamata, Masakazu, Kranz, Emiko, Lee, YooJin, Liu, Chaoyong, Liu, Yang, Lu, Yunfeng, Martinez-Maza, Otoniel, Qin, Meng, Sun, Guibo, Sun, Xiaobo, Vinters, Harry V, Wang, Lan, Wen, Jing, Widney, Daniel, Wu, Di, Xu, Duo   +17 more
core