Results 161 to 170 of about 53,910 (306)

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

A comprehensive overview of strategies to improve blueberry fruit quality. [PDF]

Front Plant Sci
Lopes T, Silva AP, Vicente AA, Gonçalves B.   +3 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Earthquake firmness of the reconstructed buildings of middle floor

, 2012
With introduction to the action of new normative document on building in seismic districts the areas of territories of Ukraine, being dangerous in a seismic relation, broadened considerably. During rekonstruk-cii of model dwellings buildings providing of
Morozova, E.
core  

Field assessment of brix and firmness affecting Drosophila suzukii (Diptera: Drosophilidae) infestation in California sweet cherry cultivars. [PDF]

J Econ Entomol
Buck N, Gress BE, Zalom FG.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Determining Applications of Intermediate Wheatgrass in Conjunction With Common Wheat: Assessing Affects on Functionality and Digestibility. [PDF]

J Food Sci
Ferguson MJ, Cattani D, Fu BX, Wang K, Malalgoda M.   +4 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Evaluation of tactile sensors in apple firmness measurement

, 2001
peer reviewedThe objective of the work consists to develop a non-destructive fruit firmness measurement. The tactile sensor technology was chosen. The force measurement acting between the fruit-sensor as well as the contact area are coupled with other ...
Petit, Catherine, Destain, Marie-France, Kleynen, Olivier, Leemans, Vincent   +3 more
core  

Cold storage delays peach fruit softening via m⁶A reader PpYTHDFE1 liquid-liquid phase separation-mediated degradation of cell wall-loosening transcript PpEXP3. [PDF]

Mol Hortic
Wang H, Bian H, Wu X, Chen K, Grierson D, Zhang B.   +5 more
europepmc   +1 more source