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Mental disorders in first‐degree relatives of schizophrenics

Acta Psychiatrica Scandinavica, 1991
A total 215 first‐degree relatives of 88 twin probands with schizophrenia, mood disorders and nonaffective psychoses were studied. The twins’ parents and siblings were personally interviewed with structured diagnostic instruments and diagnosed in accordance with DSM‐III‐R criteria.
S, Onstad   +4 more
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Thyroid antibodies: A study of first degree relatives

Clinical Genetics, 1972
A study has been made of the presence of thyroid antibodies in the relatives of a random sample of elderly subjects, not selected on the basis of a thyroid disorder. The presence of antibodies was tested by the tanned red cell technique. The results suggest that the ability to form antibodies is under polygenic control and is of moderate heritability ...
R, Hall, P R, Dingle, D F, Roberts
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Sellar abnormalities in female first-degree relatives

Clinical Neurology and Neurosurgery, 2008
Non-pituitary lesions account for a minority of sellar region abnormalities. We report the unusual occurrence of non-pituitary sellar/suprasellar lesions in a mother and her two daughters. Each of these cases was diagnosed and managed differently, illustrating the relative importance of radiographic imaging, tumor markers and histopathologic ...
Darlene, Gabeau-Lacet   +4 more
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Getting the first degree relatives to screen for colorectal cancer is harder than it seems—patients’ and their first degree relatives’ perspectives

International Journal of Colorectal Disease, 2017
First degree relatives (FDR) of colorectal cancer (CRC) patients are at increased risk of CRC compared to the general population. However, screening colonoscopy rates amongst the FDRs remain dismal. The aim of the study was to explore the various issues amongst the patients and their FDR precluding their adoption of screening colonoscopy.A qualitative ...
Ker-Kan Tan   +7 more
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Psychiatric Morbidity in the First-Degree Relatives of Schizophrenic Patients

British Journal of Psychiatry, 1993
First-degree relatives (FDRs) of 1018 schizophrenic and 812 control probands were investigated. Psychiatric morbidity was present in 34.8% of FDRs of schizophrenic probands and in 9.2% of FDRs of controls. There was significantly more psychiatric illness in the siblings and parents than in the offspring of both schizophrenic and control subjects.
S L, Varma, I, Sharma
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Alcoholic men with no alcoholic first-degree relatives

American Journal of Psychiatry, 1983
The author ascertained the family history of alcoholism in first-degree relatives and extended family members from interviews with 161 men with primary alcoholism consecutively admitted to an inpatient treatment program, as well as from one or two resource persons for each patient. Although 56% (N = 90) of the patients reported no history of alcoholism
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Autoimmune diseases in patients with pemphigus and their first‐degree relatives

International Journal of Dermatology, 2011
AbstractBackground  Pemphigus is an autoimmune blistering disease affecting the skin and mucosa, which mostly in anecdotal reports has been associated with several autoimmune diseases.Objective  The aim of this study was to assess the frequency of autoimmune diseases in a large group of patients with pemphigus and their first‐degree relatives.Methods ...
Yael A, Leshem   +4 more
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Lymphoma in patients with dermatitis herpetiformis and their first-degree relatives

British Journal of Dermatology, 2005
The risk for lymphoma is increased in both dermatitis herpetiformis (DH) and in coeliac disease. The lymphoma most associated with coeliac disease is enteropathy-associated T-cell lymphoma.To study the occurrence and type of lymphoma in a large series of patients with DH and their first-degree relatives.The occurrence of lymphoma was studied in 1104 ...
K, Hervonen   +4 more
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Serotonin Relationships of Autistic Probands and Their First-Degree Relatives

Journal of the American Academy of Child Psychiatry, 1985
Thirty autistic children and 84 of their first-degree relatives were examined for serotonin blood levels and platelet counts. Among the autistic children, boys have higher serotonin blood levels than girls. Furthermore, autistic boys have higher levels than fathers, but have levels resembling those of their siblings.
S, Kuperman   +3 more
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Bipolar II disorders in six first-degree relatives

Biological Psychiatry, 1993
As proposed by Dunner et al (1976), the distinction of bipolar !! disorder from other effective disorders has been included in Research Diagnostic Criteria (RDC) (Spitzer et al 1978) but not in DSM-IiI-R or ICD 10 (APA 1987, WHO 1991). Family studies indicate that bipolar 1I disorder might represent a distinct diagnostic entity with a common genetic ...
R, Heun, W, Maier
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