European Psychiatry, 2022 Introduction Family studies provide the opportunity to investigate endophenotypes as a powerful neurobiological platform to better understand the underlying neurobiological mechanisms of schizophrenia spectrum disorders.
R. Ayesa-Arriola +5 more
doaj +1 more source
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2022 Background Social cognition is a multi-factorial construct defined as the ability to process social information for adaptive functioning. A large body of evidence acknowledges deficits in social cognition as important features in schizophrenia and that ...
Lamis A. El Ray +3 more
doaj +1 more source
Anti-Saccharomyces cerevisiae antibodies in patients with inflammatory bowel disease and their first-degree relatives: Potential clinical value [PDF]
, 2002 Anti-Saccharomyces cerevisiae antibodies (ASCA) have been described as specific markers in Crohn's disease and their healthy first-degree relatives. 171 patients with Crohn's disease, their 105 first-degree relatives, 145 patients with ulcerative colitis
Török, H.-P. +5 more
core +1 more source
Serum antibodies in first-degree relatives of patients with IBD: A marker of disease susceptibility? A follow-up pilot-study after 7 years [PDF]
, 2005 Introduction: Various disease-specific serum antibodies were described in patients with inflammatory bowel disease and their yet healthy first-degree relatives.
Török, H.-P. +9 more
core +1 more source
Surveillance Outcomes in Patients With a Family History of Colorectal Cancer in Both Parents
Gastro Hep Advances, 2023 Background and Aims: A family history of colorectal cancer (CRC) in a first-degree relative is a well-established risk factor for CRC. When individuals have 2 parents with CRC, the impact on risk is uncertain, and there are no established guidelines for ...
Dan Feldman +2 more
doaj +1 more source
Anhedonia is associated with blunted reward sensitivity in first-degree relatives of patients with major depression [PDF]
, 2016 BACKGROUND: Anhedonia is a cardinal feature of major depression and is hypothesized to be driven by low motivation, in particular blunted reward sensitivity.
Roiser, JP +22 more
core +1 more source
ANXIETY AMONG FIRST DEGREE RELATIVE OF SURGICAL PATIENTS AT FAUJI FOUNDATION HOSPITAL
Pakistan Armed Forces Medical Journal, 2020 Objective: To ingress the austerity of symptoms of anxiety of the first-degree relatives that report to the hospital at the time at which their relative has to go a surgical procedure. Study Design: Cross sectional study.
Dujanah Siddique Bhatti +3 more
doaj +2 more sources
P300 in first degree relatives of schizophrenics
Schizophrenia Research, 1991 It has been reported that the amplitude of P300 is low in schizophrenic patients and high risk children. We recorded P300 components of the event-related potentials in first degree relatives of schizophrenic propositi who were considered to be over the age limit of the risk period for manifestation of schizophrenia and compared them with those of ...
Y, Kidogami +3 more
openaire +3 more sources
Specific insulin and proinsulin in normal glucose tolerant first-degree relatives of NIDDM patients
Brazilian Journal of Medical and Biological Research, 1999 In order to identify early abnormalities in non-insulin-dependent diabetes mellitus (NIDDM) we determined insulin (using an assay that does not cross-react with proinsulin) and proinsulin concentrations.
R. Coifman +3 more
doaj +1 more source
Incidence rates of dilated cardiomyopathy in adult first-degree relatives versus matched controls
International Journal of Cardiology: Heart & Vasculature, 2022 Background: The incidence rates and importance of traditional risk factors in dilated cardiomyopathy among first-degree relatives are unknown. Methods and Results: We identified all probands with dilated cardiomyopathy (n = 13,714, mean age at diagnosis ...
Charlotte Andersson +10 more
doaj +1 more source