Results 51 to 60 of about 16,184,258 (301)

Metabolite Alterations in Adults With Schizophrenia, First Degree Relatives, and Healthy Controls: A Multi-Region 7T MRS Study

Frontiers in Psychiatry, 2021
Proton magnetic resonance spectroscopy (MRS) studies in schizophrenia have shown altered GABAergic, glutamatergic, and bioenergetic pathways, but if these abnormalities are brain region or illness-stage specific is largely unknown.
S. Andrea Wijtenburg, Min Wang, Stephanie A. Korenic, Shuo Chen, Peter B. Barker, Peter B. Barker, Laura M. Rowland   +6 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

The effects of childhood trauma on personality in unaffected first-degree relatives of patients with major depressive disorder

BMC Psychiatry, 2022
Abstrac Objectives This study aimed to preliminarily and exploratorily examine the associations between childhood trauma (CT), its subtypes, and personality traits among unaffected first-degree relatives (FDR, children, or siblings) of patients with ...
Yu-jie Wen, Qi-jing Bo, Wen-peng Hou, Zhen Mao, Feng Li, Fan He, Fang Dong, Xin Ma, Yi-lang Tang, Xian-bin Li, Chuan-yue Wang   +10 more
doaj   +1 more source

Periodontitis in First Degree-Relatives of Individuals With Rheumatoid Arthritis: A Short Narrative Review

Frontiers in Oral Health, 2022
Periodontal disease (PD) and rheumatoid arthritis (RA) are chronic inflammatory diseases with a bi-directional relationship. Both share common genetic and environmental risk factors and result in the progressive destruction of bone and connective tissue.
Alkisti Zekeridou, Benoit Gilbert, Axel Finckh, Catherine Giannopoulou   +3 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

A review of prostate-specific antigen screening prevalence and risk perceptions for first-degree relatives of men with prostate cancer

, 2009
First-degree relatives of men with prostate cancer have a higher risk of being diagnosed with prostate cancer than men without a family history. The present review examines the prevalence and predictors of testing in first-degree relatives, perceptions ...
P.D. BAADE, S. OCCHIPINTI, Gardiner, Robert, M.E. MCDOWELL, Gardiner, R.A., Steginga, S.K., Baade, Peter, Baade, PD, Occhipinti, S, McDowell, M.E., Occhipinti, S., Occhipinti, Stefano, Gardiner, RA, S.K. STEGINGA, Steginga, Suzanne, McDowell, ME, Steginga, SK, McDowell, Michelle, R.A. GARDINER, Baade, P.D.   +19 more
core   +1 more source

Impaired top-down modulation of saccadic latencies in patients with schizophrenia but not in first-degree relatives [PDF]

, 2015
Impaired eye movements have a long history in schizophrenia research and meet the criteria of a reliable biomarker. However, the effects of cognitive load and task difficulty on saccadic latencies (SL) are less understood.
Simon eSchwab, Miriam eJost, Miriam Jost, Schwab, Simon, Jost, Miriam, Altorfer, Andreas, Andreas eAltorfer, Simon Schwab, Andreas Altorfer, Jost M, Altorfer A, Schwab S   +11 more
core   +3 more sources

Psoriasis in first-degree relatives of psoriatic twins

Acta Dermato-Venereologica, 1984
Analysis of the presence of psoriasis in all first-degree relatives of psoriatic twin probands, 38 monozygotic (MZ) and 24 dizygotic (DZ), has been performed in order to clarify if genetic heterogeneity might be present (the twin-family method). The probands were derived from a population based sample of like-sexed twin pairs.
openaire   +3 more sources

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

A comparative study on neurological soft signs in patients suffering from schizophrenia, their first-degree relatives and healthy control

Telangana Journal of Psychiatry, 2021
Introduction: Neurological soft signs (NSS) can be defined as a group of minor nonlocalizable neurological abnormalities, including simple motor coordination, complex motor sequencing, and sensory integration dysfunctions. Research has postulated complex
Durva Balkrishna Sail, Sneh Babhulkar, Nitesh H Mishra, Krishna Kadam, Prasanna Vinayak Phutane, Akash Kumar Nema, Pooja Dubey   +6 more
doaj   +1 more source