First-line treatment of acute lymphoblastic leukemia with pegasparaginase [PDF]
Riccardo Masetti, Andrea PessionPediatric Oncology and Hematology Unit “Lalla Seràgnoli”, University of Bologna, Bologna, ItalyAbstract: Acute lymphoblastic leukemia (ALL) accounts for almost 4000 cases annually in the ...
Riccardo Masetti, Andrea Pession
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Role of erlotinib in first-line and maintenance treatment of advanced non-small-cell lung cancer
Noemí Reguart1, Andrés Felipe Cardona2, Rafael Rosell31Medical Oncology Service, ICMHO, Hospital Clinic Barcelona, Barcelona, Spain; 2Clinical and Translational Oncology Group, Institute of Oncology, Fundación Santa Fe de
Noemí Reguart +2 more
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Mohammed Biset Ayalew,1 Dawit Kumilachew,2 Assefa Belay,3 Samson Getu,4 Derso Teju,4 Desalegn Endale,4 Yemisirach Tsegaye,4 Zebiba Wale4 1Department of Clinical Pharmacy, 2Department of Pharmaceutics, 3Department of Pharmacology, 4School of Pharmacy ...
Ayalew MB +7 more
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Unfinished first-line tuberculosis treatment in primary care in Indonesia [PDF]
Background. Unfinished tuberculosis (TB) treatment has slowly but surely become an unexpected event in the disease’s development into drug-resistant TB.
Al Asyary, Yodi Mahendradhata
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Neha Gupta, Hassan Hatoum, Grace K DyDepartment of Medicine, Roswell Park Cancer Institute, Buffalo, NY, USAAbstract: Lung cancer is the leading cause of cancer mortality worldwide in both men and women.
Gupta N, Hatoum H, Dy GK
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Mycophenolate Mofetil for First-Line Treatment of Immune Thrombocytopenia [PDF]
BACKGROUND: Immune thrombocytopenia (ITP) is a rare autoimmune thrombocytopenia with associated bleeding risk and fatigue. Recommended first line ITP treatment is with high dose glucocorticoids but side effects, heterogeneous responses and high relapse ...
Talks, Kate +27 more
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First‐Line Treatment for Hypertension [PDF]
Expert recommendations have until nowfocused on comparative analyses of cardiovascularoutcomes, efficacy in reducing blood pressure (BP),adverse effects, and cost. Essential hypertension can beclassified into distinct subtypes depending on the pri-mary hemodynamic derangement, which can either beincreased cardiac output (CO), as is more commonlyseen in ...
Stewart Siu-Wa, Chan +2 more
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Cost-effectiveness of tenofovir instead of zidovudine for use in first-line antiretroviral therapy in settings without virological monitoring. [PDF]
BACKGROUND: The most recent World Health Organization (WHO) antiretroviral treatment guidelines recommend the inclusion of zidovudine (ZDV) or tenofovir (TDF) in first-line therapy.
Alec Miners +31 more
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Effective second-line treatment with cetuximab and bevacizumab in a patient with hepatic metastases of colorectal cancer and hyperbilirubinemia [PDF]
Background: Irinotecan-based second-line chemotherapy of metastatic colorectal cancer (CRC) is effective, it might, however, be contraindicated in cases of severe liver dysfunction due to advanced liver metastases.
Moosmann, Nicolas +4 more
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First-Line Biological Agents Plus Chemotherapy in Older Patients with Metastatic Colorectal Cancer: A Retrospective Pooled Analysis. [PDF]
Biologicals, in combination with chemotherapy, are recommended as first-line treatment of metastatic colorectal cancer (mCRC); however, evidence guiding the appropriate management of older patients with mCRC is limited.
Vieitez, Jose Maria +20 more
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