Results 1 to 10 of about 2,053,288 (119)
Efficacy of second-line treatment for gemcitabine-refractory unresectable pancreatic cancer in a real-world setting [PDF]
BMC CancerBackground This study aimed to compare the benefits and identify the best second-line treatment regimen for gemcitabine-refractory unresectable pancreatic cancers.
Qianqian Wang +9 more
doaj +2 more sources
Clinical audit of current Helicobacter pylori treatment outcomes in Singapore
Singapore Medical Journal, 2022 Introduction: H. pylori eradication reduces the risk of gastric malignancies and peptic ulcer disease. First-line therapies include 14-day PAC (proton pump inhibitor [PPI], amoxicillin, clarithromycin) and PBMT (PPI, bismuth, metronidazole, tetracycline).
Tiing Leong Ang +5 more
doaj +1 more source
Frontiers in Oncology, 2022 AimsThis study aimed to observe the efficacy and safety of anlotinib in the treatment of small cell lung cancer (SCLC) in the real world, as first-line maintenance therapy, second-line, and above.MethodsClinical data of 109 patients with SCLC treated ...
Jing Yuan +4 more
doaj +1 more source
Second-line treatment options in hepatocellular carcinoma
Drugs in Context, 2019 For many years, sorafenib has been the only approved systemic treatment for advanced hepatocellular carcinoma (HCC). For over a decade, randomized controlled trials exploring the efficacy of new drugs both in first- and second-line treatment have failed ...
Donatella Marino +4 more
doaj +1 more source
Frontiers in Oncology, 2023 Hepatocellular carcinoma (HCC) is a tumor with a high degree of malignancy. Patients have poor outcomes and short survival times, especially after progression to first-line systemic therapy.
Yanzhi Wan, Hong Zhu
doaj +1 more source
Chemotherapy in Pancreatic Cancer: A Systematic Review
Medicina, 2018 Background and Aim: Pancreatic cancer is one of the most fatal cancers. Cytotoxic chemotherapy remains the mainstream treatment for unresectable pancreatic cancer.
Leva Hajatdoost +4 more
doaj +1 more source
Antibiotics, 2020 The management of Helicobacter pylori infection has to rely on previous local effectiveness due to the geographical variability of antibiotic resistance. The aim of this study was to evaluate the effectiveness of first and second-line H. pylori treatment
María Caldas +49 more
doaj +1 more source
Frontiers in Oncology, 2022 ObjectiveThe purpose of this study is to determine the efficacy and safety of lenvatinib as second-line therapy in Chinese patients with unresectable hepatocellular carcinoma (HCC).MethodsWe performed a retrospective analysis of Chinese patients with ...
He-nan Qin +6 more
doaj +1 more source
Медицинский совет, 2019 The low efficacy of cytostatic therapy in mGC led to an active study of the role of molecular targets in the carcinogenesis of GC. Ramucirumab is the only neoangiogenesis inhibitor, which demonstrated its antitumor activity both as monotherapy and in ...
T. A. Titova +2 more
doaj +1 more source
The Pan African Medical Journal, 2020 Pre-extensively drug resistant tuberculosis (pre-XDR-TB) has been an area of growing concern, and posing a threat to global efforts of TB control. We report a case of PreXDR-TB spondylodiscitis with resistance to a Fluoroquinolone, in an immunocompetent ...
Safaa Fellous +5 more
doaj +1 more source