Second-Line Treatment for Pancreatic Cancer [PDF]
Although standard of care for treatment of pancreatic cancer is established in the first line setting, there is limited data to support standard for second line chemotherapy for advanced pancreatic cancer. This is starting to change, as new studies have shown positive effect on overall survival in the second line setting.
Nancy, Kaddis, Muhammad Wasif, Saif
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Second-line Treatment for Faecal Incontinence
In the treatment of faecal incontinence, more than 30% of patients experience continuation of their problem. We discuss new therapeutic procedures for dealing with faecal incontinence.Discussion of authors' own work in relation to the literature.First-line care includes diets, constipating drugs, biofeedback therapy, anal repair and operations for ...
Baeten, C.G.M.I., Uludag, Ö
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Economic evaluation of eribulin as second-line treatment for metastatic breast cancer in South Korea
Gabriel Tremblay,1 Unnati Majethia,2 Janis L Breeze,3 Ilias Kontoudis,4 Jeongae Park5 1Geneconomics Inc., Lévis, Quebec, Canada; 2Global Value and Access, Eisai Inc., Woodcliff Lake, NJ, 3Tufts Clinical and Translational Science Institute, Tufts ...
Tremblay G +4 more
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Bjoern Schwander,1 Simona Ravera,2 Giovanni Giuliani,2 Mark Nuijten,3 Stefan Walzer11Assessment-in-Medicine (AiM) GmbH, Loerrach, Germany; 2Roche SpA, Monza, Italy; 3Ars Accessus Medica, Amsterdam (Jisp), NetherlandsBackground: Lung cancer is the leading
Schwander B +4 more
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Sirolimus as a Second-Line Treatment for Graves’ Orbitopathy
Background: A beneficial effect of sirolimus in Graves’ orbitopathy (GO) was reported, suggesting its possible use in clinical practice.Methods Observational, single-centre, no-profit, clinical study to investigate the efficacy of sirolimus as a second-line treatment for moderate-to-severe, active GO compared with methylprednisolone. &
Lanzolla, G +8 more
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Second-Line Treatment of Ovarian Cancer [PDF]
Abstract Patients with epithelial ovarian cancer are often diagnosed with advanced-stage disease. Although clinical complete remissions are obtained in the majority of patients through a combination of cytoreductive surgery and chemotherapy, relapse is common.
M, Markman, M A, Bookman
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Second-line treatment for renal cell cancer [PDF]
In metastatic renal cell carcinoma (mRCC), the transition to the targeted therapy era has made available a variety of effective new agents, including vascular endothelial growth factor tyrosine kinase receptor (VEGF-TKR) inhibitors, such as sunitinib, pazopanib, sorafenib; anti-VEGF monoclonal antibody bevacizumab; and mTOR (mammalian target of ...
Di Lorenzo, G +2 more
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Immunological failure of first-line and switch to second-line antiretroviral therapy among HIV-infected persons in Tanzania: analysis of routinely collected national data. [PDF]
OBJECTIVES: Rates of first-line treatment failure and switches to second-line therapy are key indicators for national HIV programmes. We assessed immunological treatment failure defined by WHO criteria in the Tanzanian national HIV programme. METHODS: We
Ramadhani, Angela +6 more
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Tenofovir in second-line ART in Zambia and South Africa: collaborative analysis of cohort studies. [PDF]
Article approval pendingTenofovir (TDF) is increasingly used in second-line antiretroviral treatment (ART) in sub-Saharan Africa. We compared outcomes of second-line ART containing and not containing TDF in cohort studies from Zambia and the Republic of ...
Brennan, Alana +39 more
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Mycophenolate mofetil as second line treatment in autoimmune hepatitis – A retrospective single center analysis [PDF]
Background: Most patients with autoimmune hepatitis respond to standard treatment with steroids and azathioprine. While the disease is usually fatal if untreated, patients who respond well to therapy have an excellent prognosis. Nevertheless, second-line
Annalisa Berzigotti +14 more
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