Results 91 to 100 of about 2,599,230 (282)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Novel, Synchronous, First-person Perspective Virtual Simulations for Medical Students in Emergency Medicine. [PDF]
West J Emerg Med, 2023 Sperandeo M +4 more
europepmc +1 more source
Authenticity and the third-person perspective [PDF]
, 2015 In this paper, I argue for two claims: first, that authenticity is a property possessed only by those preferences and commitments whose satisfaction contributes to our lives going well; and secondly, that our preferences are authentic just in case they ...
Colburn, Ben
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FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Human Persons as Social Entities
Journal of Social Ontology, 2014 The aim of this article is to show that human persons belong, ontologically, in social ontology. After setting out my views on ontology, I turn to persons and argue that they have first-person perspectives in two stages (rudimentary and robust ...
Lynne Rudder Baker
doaj
Metacognition and Decision Making: between First and Third Person Perspective [PDF]
Interdisciplinary Description of Complex Systems, 2012 The aim of the article is firstly, to show how metacognitive monitoring, control (regulation) and meta-knowledge are important in guiding decision making and secondly, to argue that researching experience is necessary for a more complete understanding of
Toma Strle
doaj
The Impact of Perspective Change As a Cognitive Reappraisal Strategy on Affect: A Systematic Review [PDF]
, 2016 The strategic or deliberate adoption of a cognitively distanced, third-person perspective is proposed to adaptively regulate emotions. However, studies of psychological disorders suggest spontaneous adoption of a third-person perspective reflects ...
Kamboj, SK, Wallace-Hadrill, SMA
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Towards a First-Person Perspective Mixed Reality Guidance System for Needle Interventions. [PDF]
J Imaging, 2022 Groves L, Li N, Peters TM, Chen ECS.
europepmc +1 more source
The Second-Person Standpoint in Law and Morality [PDF]
, 2014 The papers of this special issue are the outcome of a two-‐day conference entitled “The Second-‐Person Standpoint in Law and Morality,” that took place at the University of Vienna in March 2013 and was organized by the ERC Advanced Research Grant ...
Pauer-Studer, Herlinde
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