Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Selection of patients and their first-degree relatives.
Selection of patients and their first-degree relatives.
Francis Couturaud (821892) +3 more
core +1 more source
Background&Objective: Comorbidity between ADHD (Attention Deficit Hyperactivity Disorder) and major depression has been reported from both epidemiologic and clinical studies of both children and adults.
P.Hebranei (MD) +2 more
doaj
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann +8 more
wiley +1 more source
Neurological soft signs in non-psychotic first-degree relatives of patients with schizophrenia: A systematic review and meta-analysis [PDF]
Background: Neurological soft signs (NSS) have been associated with the neuropsychopathology of schizophrenia, and have been proposed as candidate endophenotypes for this clinical group.
Gong, Qi-yong +5 more
core
Risk of Dementia in First-Degree Relatives of Patients with Alzheimer's Disease and Related Disorders [PDF]
First-degree relatives of patients with Alzheimer's disease (AD) are at greater risk for dementia when compared with the relatives of their healthy peers, but not when compared with the relatives of patients with Parkinson's disease.
Sano, Mary +4 more
core +1 more source
Evaluation of the serum fasting insulin and HOMA-IR in diabetic and FDR patients [PDF]
Background: Diabetes mellitus is an endocrine disorder. It is one of the leading causes of morbidity and mortality due to its role in the development of microvascular and macrovascular complications.
Dipalee Rahul Navale +1 more
doaj
Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari +5 more
wiley +1 more source
RHD case detection among the first degree relatives according to proband status in 39 households.
RHD case detection among the first degree relatives according to proband status in 39 households.
Susy Kotit (11559042) +4 more
core +1 more source
Hyperventilation in panic disorder patients and healthy first-degree relatives
Our aim was to observe the induction of panic attacks by a hyperventilation challenge test in panic disorder patients (DSM-IV) and their healthy first-degree relatives. We randomly selected 25 panic disorder patients, 31 healthy first-degree relatives of
A.E. Nardi +5 more
doaj +1 more source

