Results 61 to 70 of about 13,597,388 (346)

Proxy measures for the assessment of psychotic and affective symptoms in studies using electronic health records

open access: yesBJPsych Open
Background There is a lack of standardised psychometric data in electronic health record (EHR)-based research. Proxy measures of symptom severity based on patients' clinical records may be useful surrogates in mental health EHR research. Aims This study
Álvaro López-Díaz   +26 more
doaj   +1 more source

A systematic review of PTSD to the experience of psychosis: prevalence and associated factors

open access: yesBMC Psychiatry, 2021
Background Psychosis can be a sufficiently traumatic event to lead to post-traumatic stress disorder (PTSD). Previous research has focussed on the trauma of first episode psychosis (FEP) and the only review to date of PTSD beyond the first episode period
Georgina Buswell   +3 more
doaj   +1 more source

Neurocognitive functioning and emotional recognition in first-episode psychosis: protocol for a follow- up study

open access: yesEuropean Psychiatry
Introduction Although deficits in neurocognitive functioning and emotional recognition impact treatment outcomes in schizophrenia since the development of the first psychotic episode (FEP), there is still a lack of longer follow-up studies showing the ...
D. Bošnjak Kuharić   +6 more
doaj   +1 more source

Oxidative Stress and Inflammation in First-Episode Psychosis: A Systematic Review and Meta-analysis.

open access: yesSchizophrenia bulletin, 2018
Despite mixed findings, increasing evidence suggests that people with first-episode psychosis (FEP) show increased pro-inflammatory and pro-oxidative status.
D. Fraguas   +7 more
semanticscholar   +1 more source

Design of the BiRmingham Early Detection In untREated psyChosis Trial (REDIRECT): cluster randomised controlled trial of general practitioner education in detection of first episode psychosis [ISRCTN87898421]

open access: yesBMC Health Services Research, 2005
Background Treatment delay in first episode psychosis is common. As general practitioners are the first point of contact for many individuals with first episode psychosis, they are well placed to detect the early symptoms and make urgent referrals to ...
Freemantle Nick   +4 more
doaj   +1 more source

First episode psychosis related to COVID-19 infection

open access: yesEuropean Psychiatry, 2022
Introduction During the course of COVID-19 pandemic, The respiratory system is the most commonly affected while many neuropsychiatric manifestations of the disease have been observed.
S. Dhakouani   +4 more
doaj   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

open access: yesAdvanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni   +17 more
wiley   +1 more source

Innate Immune Cells and C-Reactive Protein in Acute First-Episode Psychosis and Schizophrenia: Relationship to Psychopathology and Treatment

open access: yesSchizophrenia bulletin, 2019
Innate immunity has been linked to initiation of Alzheimer’s disease and multiple sclerosis. Moreover, risk of first-episode psychosis (FEP) and schizophrenia (Sz) is increased after various infections in predisposed individuals. Thus, we hypothesized an
J. Steiner   +12 more
semanticscholar   +1 more source

First-Episode Psychosis: A Clinical Approach [PDF]

open access: yesThe Journal of the American Board of Family Medicine, 2000
Psychotic illnesses, such as schizophrenia and bipolar illness, are relatively common and clearly devastating diseases. Most scientific literature focuses on research and care of patients suffering from psychotic illnesses in the middle age-group; subsequently, the first episode or early stages of psychotic illnesses have been relatively ignored ...
S C, Schulz, D, Bass, C S, Vrabel
openaire   +2 more sources

An Adult Presentation of KIF11‐Related MCLID Syndrome: Case Report and 40‐Year Follow‐Up

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic variants in KIF11 are linked to autosomal dominant syndromes with microcephaly, chorioretinopathy, lymphedema, and intellectual disability (MCLID), though adult presentations remain underreported. We report a 42‐year‐old female presenting with a de novo single‐amino acid in‐frame deletion in the KIF11 gene (c.1294_1296del; p ...
Thrishna Chathurvedula   +8 more
wiley   +1 more source

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