Results 81 to 90 of about 13,597,388 (346)

Standardization of measurement and reporting of medication adherence using the TEN‐SPIDERS tool for claims data

British Journal of Clinical Pharmacology, EarlyView.
This study provides the first open‐source tool to implement the complete TEN‐SPIDERS framework in linked datasets for the determination of the PDC for medication adherence. The TEN‐SPIDERS tool enables transparent, reproducible medication adherence research through automated reporting of all calculation parameters and flexible customization options ...
Adam C. Livori, Tzu‐Yung Kuo, Jenni Ilomäki, Monique F. Kilkenny, Stella Talic, Zanfina Ademi, J. Simon Bell, Jedidiah I. Morton, Lachlan L. Dalli   +8 more
wiley   +1 more source

Determinants of treatment response in first episode psychosis: an 18F-DOPA PET study

Molecular Psychiatry, 2018
Psychotic illnesses show variable responses to treatment. Determining the neurobiology underlying this is important for precision medicine and the development of better treatments.
S. Jauhar, M. Veronese, M. Nour, M. Rogdaki, P. Hathway, F. Turkheimer, J. Stone, A. Egerton, P. McGuire, S. Kapur, O. Howes   +10 more
semanticscholar   +1 more source

Relationships among nitrous oxide exposure, neurological injury and biomarkers

British Journal of Clinical Pharmacology, EarlyView.
Aims Recreational nitrous oxide (N2O) misuse is an increasing public health problem associated with functional cobalamin (B12) deficiency and severe neurological complications. Despite growing recognition of its harms, the dose–response relationship and clinical value of biomarkers remain unclear.
Laxna Bhujel, Angela L. Chiew, Bhashita Jagarlamudi, Pramod Chandru, Naren Gunja, Nancy Briggs, Betty S. Chan   +6 more
wiley   +1 more source

Prescribing in First Episode Psychosis

BJPsych Open
Aims This audit aimed to review prescribing in First Episode Psychosis (FEP) in Gloucestershire Health and Care NHS Trust, against NICE guidelines (CG 178) we hoped to develop prescribing guidelines for the Trust and to compare our results with Avon and
Edita Searle, Raeema Patel, Robertson Macpherson   +2 more
doaj   +1 more source

Using Machine Learning and Structural Neuroimaging to Detect First Episode Psychosis: Reconsidering the Evidence

Schizophrenia bulletin, 2019
Despite the high level of interest in the use of machine learning (ML) and neuroimaging to detect psychosis at the individual level, the reliability of the findings is unclear due to potential methodological issues that may have inflated the existing ...
S. Vieira, Q. Gong, W. H. L. Pinaya, C. Scarpazza, S. Tognin, B. Crespo-Facorro, D. Tordesillas-Gutiérrez, V. Ortiz-García, E. Setién-Suero, F. Scheepers, N. V. van Haren, T. Marques, R. Murray, A. David, P. Dazzan, P. McGuire, A. Mechelli   +16 more
semanticscholar   +1 more source

Incident low‐dose quetiapine use in adults newly diagnosed with depression in primary care: A nationwide register‐based study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to investigate the incidence of low‐dose quetiapine initiation and associated factors in adults newly diagnosed with depression in primary care. Methods We obtained medication dispensing records, primary and secondary care diagnoses and employment status for antipsychotic‐naïve individuals aged 16–65 newly diagnosed with ...
Laura Purra, Heidi Taipale, Miia Tiihonen, Markku Lähteenvuo, Jari Tiihonen, Aleksi Hamina   +5 more
wiley   +1 more source

First-episode psychosis and substance use in an acute mental health unit

South African Journal of Psychiatry, 2018
Background: Substance use is frequent among first-episode psychosis (FEP) patients, and it has prognostic implications. There is a dearth of locally published literature in the Eastern Cape, South Africa, on the prevalence of substance use amongst FEP ...
Yanga Thungana, Zukiswa Zingela, Stefan Van Wyk   +2 more
doaj   +1 more source

Psychiatric Emergency Presentations in Detained Adolescents: A Comparison With Community‐Living Adolescents

Criminal Behaviour and Mental Health, EarlyView.
ABSTRACT Background Adolescents involved in the juvenile justice system have high rates of psychiatric disorder and social vulnerability. Those in custodial or semi‐custodial detention may be particularly vulnerable to psychiatric emergencies, but the clinical factors associated with these crises remain insufficiently understood.
Maria Carolina Lobato Machado, Marcela de Moura Rezende, Izabela Lara Borém, Maria Eugênia Rezeck Braga Hibner, Danilo Barcellos Nogueira, Luciana Rodrigues da Cunha, Rodrigo Nicolato, Debora Marques de Miranda   +7 more
wiley   +1 more source

Comorbidity rates of depression and anxiety in first episode psychosis: A systematic review and meta-analysis.

Schizophrenia Research, 2019
Anxiety and depression symptoms are frequently experienced by individuals with psychosis, although prevalence rates have not been reviewed in first-episode psychosis (FEP).
Rebecca S. Wilson, A. Yung, A. Morrison
semanticscholar   +1 more source

The predictive factors of subjective recovery in first-episode psychosis. [PDF]

, 2007
Conceptualisations of recovery from psychosis have evolved over time, from medically defined models of symptom reduction, to more recent definitions of subjective recovery. First-episode psychosis (FEP) individuals present as a group who are in the early
Morland, T.
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