Results 71 to 80 of about 13,597,388 (346)
People with psychotic disorders show abnormalities in several organ systems in addition to the central nervous system (CNS); and this contributes to excess mortality. However, it is unclear how strong the evidence is for alterations in non-CNS systems at
T. Pillinger +3 more
semanticscholar +1 more source
Influence of Molecular Genetic Classes on Behavior in Prader‐Willi Syndrome
ABSTRACT A wide range of behavioral phenotypes has been described in PWS patients including autism spectrum disorder (ASD). The prevalence of behavioral disorders was studied in 292 participants over 3 years with genetically confirmed PWS (N = 164 females and N = 128 males) with deletion (N = 182) and mUPD (maternal uniparental disomy) (N = 99).
Ranim Mahmoud +6 more
wiley +1 more source
Clozapine prescribing during follow-up of a first-episode psychosis cohort
Introduction Of those with schizophrenia, one third develop treatment-resistant illness. Nearly 60% of these benefit from clozapine- the only antipsychotic medication licensed in this group.
R. Rowntree +7 more
doaj +1 more source
BACKGROUND Three out of four first-episode psychosis (FEP) patients achieve clinical remission following treatment. Unfortunately, functional recovery lags behind symptomatic remission, and many individuals with FEP remain socially isolated with poor ...
Olga Santesteban-Echarri +6 more
semanticscholar +1 more source
Helping loved ones cope and care for patients who have a lack of ...
openaire +2 more sources
Dissociation of long-term verbal memory and fronto-executive impairment in first-episode psychosis [PDF]
Background: Verbal memory is frequently and severely affected in schizophrenia and has been implicated as a mediator of poor clinical outcome. Whereas encoding deficits are well demonstrated, it is unclear whether retention is impaired.
Robbins, T. W. +15 more
core +1 more source
Extending the ATP9A‐Related Phenotypic Spectrum: Indication of Schizophrenia Susceptibility
ABSTRACT ATP9A, which belongs to the P4‐ATPase family of proteins, is involved in the efficient transport of vesicles from the Golgi apparatus to the plasma membrane, as well as the release of extracellular vesicles from human cells. In 2021, a loss‐of‐function variant of this gene was identified as being associated with a recessive neurodevelopmental ...
Camille Verebi +10 more
wiley +1 more source
Antipsychotic treatment resistance in first-episode psychosis: prevalence, subtypes and predictors
Background We examined longitudinally the course and predictors of treatment resistance in a large cohort of first-episode psychosis (FEP) patients from initiation of antipsychotic treatment. We hypothesized that antipsychotic treatment resistance is: (a)
A. Demjaha +17 more
semanticscholar +1 more source
Hypofrontality in men with first-episode psychosis [PDF]
BackgroundDecreased metabolic activity in the prefrontal cortex during cognitive activation is a recurrent finding and a likely functional marker of schizophrenia.AimsTo investigate the occurrence of hypofrontality in patients with first-episode psychosis, with or without evolution to schizophrenia.MethodWe used fluorodeoxyglucose positron emission ...
V, Molina +9 more
openaire +2 more sources
Mindfulness, self-stigma and social functioning in first episode psychosis: a brief report [PDF]
This study aimed to test the hypothesis that people with first-episode psychosis who are more mindful will have lower self-stigma, and hence better social functioning.
Mersh, L., Oliver, J., Jones, F.
core +1 more source

