Results 71 to 80 of about 14,782,076 (302)
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source
Data on production performance of 90 imported Dutch Holstein-Friesian cattle and their 127 Pakistani- born progeny from 1982 to 1991 were analyzed. The mean first lactation 305-day milk yield for imported and Pakistani-born cows was 3196.7 ± 66.36 and ...
Asad Ullah Hyder and Samee Ullah1
doaj
: The study aimed to determine whether ADG of Holstein heifers at various stages of rearing affects first and second lactation performance. Data on BW of heifers were obtained from 3 independent dairy operators (operators A, B and C) and used to ...
A. Garus-Piętak +5 more
doaj +1 more source
REGRESSION TREE ANALYSIS OF FACTORS AFFECTING FIRST LACTATION MILK YIELD OF DAIRY CATTLE
The objective of this study was to examine the effects of management and environmental effects on first lactation milk yield by means of regression tree method. Regression tree method is useful to determine the effects of several factors on specified depended variables.
Mikail, Nazire, Bakır, Galip
openaire +2 more sources
Response to somatic cell count-based selection for mastitis resistance in a divergent selection experiment in sheep [PDF]
A divergent selection experiment in sheep was implemented to study the consequences of log-transformed somatic cell score (SCS)-based selection on resistance to natural intramammary infections.
Aurel, Marie-Rose +8 more
core +1 more source
UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma +14 more
wiley +1 more source
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni +17 more
wiley +1 more source
This study offers insight into the genetic complexity of the interaction between production and reproduction in German dairy cows. The phenotypes and genotypes of 32,352 primiparous German Holstein cows were available for investigation, and datasets (DS) of similar size were generated according to their milk yield. Five distinct DS, each including more
Leopold Schwarz +4 more
openaire +4 more sources
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin +17 more
wiley +1 more source
Dairy farming is important for food and nutrition security and livelihood protection in most tropical countries. However, productivity of dairy cows is affected by many factors and is usually low on smallholder farms in tropical environments.
Erica Auguste +2 more
doaj +1 more source

