Results 91 to 100 of about 14,782,076 (302)

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

Study on Milk Production Dynamics and Major Chemical Milk Components in Brown Sire Dams of Brown Swiss-Type from the Research and Development Station for Bovine Raising - Arad

Scientific Papers Animal Science and Biotechnologies, 2023
The present work was carried out to determine the influence of lactation rank on the milk yield, fat and protein evolution. Observations were carried out on 117 lactations, as follows: 15 first lactations, 22 second lactations, 26 third lactations, 28 ...
Florin Cristian Neciu, Ludovic-Toma Cziszter, Radu Ionel Neamț, Daniela Elena Ilie, Florin Corneliu Marinescu   +4 more
doaj  

AARS1‐Mediated H3K27 Lactylation Rewires Glycolysis to Sustain Aggressive and Recurrent Bladder Cancer

Advanced Science, EarlyView.
AARS1 drives PI3K–AKT–mTOR‐dependent glycolysis in bladder cancer, promoting lactate accumulation, increased lactylation, H3K27la enrichment at the HK2 promoter, and HK2 transcription. HK2 reinforces glycolysis, sustaining a metabolic–epigenetic program associated with tumor progression, recurrence, and metastasis.
Qin Yuan, Tianbao Song, Yipeng He, Sihan Xia, Yaoqiu Huang, Wenlin He, Qin Yi, Zefeng Wang, Peihan Wang, Chenbo Huang, Linzhi Li, Zhen Yin, Fan Cheng, Weimin Yu   +13 more
wiley   +1 more source

OSCILLATION OF SOMATIC CELL COUNT IN MILK OF RECORDED COWS IN SLOVENIA IN YEARS 1997-2007 [PDF]

, 2008
Oscilacija u broju somatskih stanica (SCC) kod kontroliranih krava proučavana je u Sloveniji u razdoblju od 1997. do 2007. godine. Tijekom 5.267.264 test dana mjerenja su obavljana pretežno za simentalsku (42,4%), zatim za crno-bijelu (37,7%) i smeđu ...
M. Klopčić, M. Klinkon, Osterc, J., Klopčić, M., J. Osterc, Klinkon, M.   +5 more
core   +1 more source

Effects of preweaning calf daily gain and feed intake on first-lactation performance: A meta-analysis

Journal of Dairy Science
: This study aimed to investigate the effects of daily weight gain and feed intake of calves on first-lactation milk yield and composition using a meta-analysis. A total of 57 treatments from 18 studies were included in the study.
Wen Jiang, Jingjun Wang, Shangru Li, Shuai Liu, Yimin Zhuang, Shengli Li, Wei Wang, Yajing Wang, Hongjian Yang, Wei Shao, Zhijun Cao   +10 more
doaj   +1 more source

Evaluation of minor pathogen intramammary infection, susceptibility parameters, and somatic cell counts on the development of new intramammary infections with major mastitis pathogens [PDF]

, 2012
Major mastitis pathogens such as Staphylococcus aureus, Streptococcus uberis, Streptococcus dysgalactiae, and coliforms are usually considered more virulent and damaging to the udder than minor mastitis pathogens such as Corynebacterium spp.
Keefe, G P, Reyher, K K, Reyher, K.K. (Author), Keefe, G.P. (Author), Scholl, D T, Dohoo, I R, Dohoo, I.R. (Author), Scholl, D.T. (Author)   +7 more
core   +1 more source

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Reproductive performance in high-producing dairy cows [PDF]

, 2008
Milk yields >10,000 kg/year are common in modern dairy production, owing to improved nutrition, management and genetic gains through use of progeny-tested bulls.
Rodriguez-Martinez, Heriberto, Bergqvist, Ann-Sofi, Bergsten, Christer, Håård, Margareta, Svenssson, Catharina, Lindhé, Bengt, Emanuelson, Ulf, Lidfors, Lena, Gunnarsson, Stefan, Båge, Renée, Algers, Bo, Gustafsson, Hans, Stålhammar, Hans, Andersson, Göran, Hultgren, Jan, Berglund, Britt   +15 more
core   +1 more source

APPLICATION OF PRINCIPAL COMPONENT ANALYSIS FOR EVALUATING FIRST LACTATION TRAITS IN CROSSBRED CATTLE [PDF]

Exploratory Animal and Medical Research
This study aimed to reduce redundancy among first lactation traits and identify key factors influencing production and reproduction in crossbred cows. Measurements were taken on 529 crossbred cattle (62.5% HF×37.5% Sahiwal) over a 30-year period (1990 ...
Simran Kaur
doaj   +1 more source

Characterization of proteins and fatty acid composition in galapagos fur seal milk. Occurrence of whey and casein protein polymorphisms [PDF]

, 1988
Trillmich F, Kirchmeier D, Kirchmeier O, et al. Characterization of proteins and fatty acid composition in galapagos fur seal milk. Occurrence of whey and casein protein polymorphisms.
Seewald, Markus, Kirchmeier, Otto, Seewald, M., Trillmich, Fritz ; https://orcid.org/, Trillmich, F., Scherz, H., Kirchmeier, Dorothea, Lechner, Erika, Scherz, Heimo, Lechner, E., Kirchmeier, O., Krause, I., Kirchmeier, D., Eichinger, Hans, Krause, Ingolf, Eichinger, H.   +15 more
core   +1 more source