Results 121 to 130 of about 3,043,670 (297)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Gagged and Doxed: Hacktivism’s Self-Incrimination Complex

International Journal of Communication, 2016
The investigation, arrest, and conviction of a number of high-profile hacker-activists, or hacktivists, reveal the ways subjectivity is mobilized through processes of revelation and evasion.
Adam Fish, Luca Follis
doaj  

Associations of Prenatal Mercury Exposure From Maternal Fish Consumption and Polyunsaturated Fatty Acids With Child Neurodevelopment: A Prospective Cohort Study in Italy

, 2013
Francesca Valent, Marika Mariuz, Maura Bin, D rsquo Anna Little, Darja Mazej, Veronica Tognin, Janja Snoj Tratnik, Alison J. McAfee, Maria S. Mulhern, Maria Parpinel, Marco Carrozzi, Milena Horvat, Giorgio Tamburlini, Fabio Barbone   +13 more
openalex   +2 more sources

Impact of fish farming facilities on Posidonia oceanica meadows: a review [PDF]

, 2006
Christine Pergent-Martinì, Charles‐François Boudouresque, Vanina Pasqualini, Gérard Pergent   +3 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Variability in frontal zone formation and distribution of gadoid fish larvae at the shelf break in the northeastern North Sea [PDF]

, 1999
Peter Munk, PO Larsson, DS Danielssen, Erlend Moksness   +3 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Brewers’ Yeast (Saccharomyces cerevisiae) Purified Functional Feed Additives Mitigate Soybean Meal-Induced Enteritis in Atlantic Salmon (Salmo salar) Parr

Aquaculture Nutrition
Soybean meal (SBM) is commonly used in aquafeeds due to its wide availability, reasonable protein content, and cost-effectiveness. However, high SBM inclusion levels in the diets of carnivorous fish, such as Atlantic salmon (Salmo salar), can cause ...
Taofik A. Momoh, Sheu Gbolahan Odu-Onikosi, Folasade Damilola Amulejoye, Joshua Wilson, Benjamin Eynon, Holger Kühlwein, Victor Kuri, Daniel L. Merrifield   +7 more
doaj   +1 more source

Impoundment impact on populations of facultative riverine fish [PDF]

, 2003
Andrzej Kruk, T. Penczak
openalex   +1 more source