Results 61 to 70 of about 3,056,976 (349)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Calibrating minimum counts and catch‐per‐unit‐effort as indices of moose population trend

Wildlife Society Bulletin, 2016
Monitoring wildlife population trends often involves indices assumed to correlate in proportion to abundance. We used aerial count data and harvest statistics for moose (Alces alces) populations in 16 hunting districts of Montana, USA, spanning 32 years (
Nicholas J. DeCesare, Jesse R. Newby, Vanna J. Boccadori, Tonya Chilton‐Radandt, Tim Thier, Dean Waltee, Kevin Podruzny, Justin A. Gude   +7 more
doaj   +1 more source

Regional African stock markets indices

South African Journal of Business Management, 2002
This paper presents an overview of the construction of regional indices for three of the four regions within Africa. The three indices are the EASDEX (for East Africa), the NADEX (for North Africa) and the WADEX (for West Africa).
T. Fish, N. Biekpe
doaj   +1 more source

Fish assemblages associated with natural and anthropogenically-modified habitats in a marine embayment: Comparison of baited videos and opera-house traps [PDF]

, 2013
Marine embayments and estuaries play an important role in the ecology and life history of many fish species. Cockburn Sound is one of a relative paucity of marine embayments on the west coast of Australia.
Coutts, T.B., Fairclough, D.V., Langlois, T.J., Lewis, P.D., Wakefield, C.B.   +4 more
core   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Myth debunked: Keratinous pangolin scales do not contain the analgesic tramadol

Conservation Science and Practice, 2019
Conservation plans aiming to reduce the threat of illegal wildlife trade increasingly recognize the need for multifaceted approaches that include both enhanced enforcement and demand reduction initiatives.
Rachel L. Jacobs, Pamela J. McClure, Barry W. Baker, Edgard O. Espinoza   +3 more
doaj   +1 more source

Fish assemblages found in tidal-creek and seagrass habitats in the Suwannee River estuary [PDF]

, 2006
Fish assemblages were investigated in tidal-creek and seagrass habitats in the Suwannee River estuary, Florida. A total of 91,571 fish representing 43 families were collected in monthly seine samples from January 1997 to December 1999.
Dehaven, Mark, Tuckey, Troy D.
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Cost-Effective Approach to Reducing Collisions with Elk by Fencing Between Existing Highway Structures

Human-Wildlife Interactions, 2017
Collisions with large ungulates cause serious human and animal injuries and significant property damage. Therefore, wildlife crossing structures are increasingly included in new road construction to reduce wildlife–vehicle collisions, while still ...
Jeffrey W. Gagnon, Chad D. Loberger, Scott C. Sprague, Kari S. Ogren, Susan L. Boe, Raymond E. Schweinsburg   +5 more
doaj   +1 more source