Results 61 to 70 of about 3,043,670 (297)

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Calibrating minimum counts and catch‐per‐unit‐effort as indices of moose population trend

open access: yesWildlife Society Bulletin, 2016
Monitoring wildlife population trends often involves indices assumed to correlate in proportion to abundance. We used aerial count data and harvest statistics for moose (Alces alces) populations in 16 hunting districts of Montana, USA, spanning 32 years (
Nicholas J. DeCesare   +7 more
doaj   +1 more source

Dual Mode Logic—Design for Energy Efficiency and High Performance

open access: yesIEEE Access, 2013
The recently proposed dual mode logic (DML) gates family enables a very high level of energy-delay optimization flexibility at the gate level. In this paper, this flexibility is utilized to improve energy efficiency and performance of combinatorial ...
Itamar Levi, Alexander Fish
doaj   +1 more source

Rapid recreation assessment: a tool to assess visitor use and associated impacts at coastal and marine protected areas [PDF]

open access: yes, 2006
As more people discover coastal and marine protected areas as destinations for leisure-time pursuits, the task of managing coastal resources while providing opportunities for high quality visitor experiences becomes more challenging.
Denny, Christine, Fish, Thomas E.
core  

Queerying activism through the lens of the sociology of everyday life [PDF]

open access: yes, 2018
The approaching 30th anniversary of the introduction of the 1988 Local Government Act offers an opportunity to reflect on the nature of lesbian, gay and bisexual (LGB) activism in Britain. The protests against its implementation involved some of the most
Almack, Kathryn   +2 more
core   +3 more sources

Robust segmentation of underwater fish based on multi-level feature accumulation [PDF]

open access: gold, 2022
Adnan Haider   +4 more
openalex   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Myth debunked: Keratinous pangolin scales do not contain the analgesic tramadol

open access: yesConservation Science and Practice, 2019
Conservation plans aiming to reduce the threat of illegal wildlife trade increasingly recognize the need for multifaceted approaches that include both enhanced enforcement and demand reduction initiatives.
Rachel L. Jacobs   +3 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Incremental events in the construction of sambaquis, southeastern Santa Catarina.

open access: yesRevista do Museu de Arqueologia e Etnologia, 2000
Moundbuilding is a cross-cultural phenomenon of nearly world-wide scope. In this article some of the moundbuilding processes related to the sambaquis (shellmounds) from the coast of Santa Catarina State, Brasil, are examined, focusing on field research ...
Suzanne K. Fish   +3 more
doaj   +1 more source

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