Results 51 to 60 of about 591,916 (369)

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

Fish Food and Fish Diseases

open access: yesJournal of Fisheries & Livestock Production, 2017
Without too technical information we will explain what we experienced during our 40+ years of feeding ornamental fish at wholesale level. In the early 90s, during our daily practice, we had 1 goal: using a complete food for ornamental fish that would provide high quality fish within 3-7 days, depending on the origin and quality of the fish. Next to the
openaire   +2 more sources

A blend of chitosan-vitamin C and vitamin E nanoparticles robust the immunosuppressed- status in Nile tilapia treated with salt

open access: yesBMC Veterinary Research
In aquaculture, fish are exposed to many stressors, such as climate changes and infectious diseases that affect their performance, immunity, and welfare. Freshwater fish subjected to salt bath become exhausted and stressed.
Mahmoud A. Elnagar   +3 more
doaj   +1 more source

A PRELIMINARY STUDY OF THE PREVALENCE OF ANTIBODIES TO INFECTIOUS BURSAL DISEASE IN BROILER CHICKENS

open access: yesThe Iraqi Journal of Veterinary Medicine, 1987
Infectious bursal disease is one of the diseases frequently diagnosed in broilers chickens in _ Iraq depending on pathological changes in the bursa of Fabricius. It is known that maternal antibodies may interfere with the clinical signs, severity of the
M. A. Al-Attar , K. K. Salman
doaj   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Distribution of choline acetyltransferase (ChAT) immunoreactivity in the brain of the teleost cyprinus carpio [PDF]

open access: yes, 2018
Cholinergic systems play a role in basic cerebral functions and its dysfunction is associated with deficit in neurodegenerative disease. Mechanisms involved in human brain diseases, are often approached by using fish models, especially cyprinids, given ...
Casini, Arianna   +3 more
core   +2 more sources

Streptococcus dysgalactiae: An emerging pathogen of fishes and mammals

open access: yesInternational Journal of Veterinary Science and Medicine, 2013
Streptococcus dysgalactiae subsp. dysgalactiae (GCSD) has gained special interest of aquatic health experts throughout the past few years due to its interesting veterinary and public health importance.
Mohamed Abdelsalam   +2 more
doaj   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Occurrence of virulence factors and antimicrobial susceptibility of Citrobacter freundii isolated from diseased ornamental fish in Poland

open access: yesJournal of Veterinary Research
Citrobacter freundii strains, like other representatives of the same genus, are often described as aetiological factors of diseases in humans and animals, including farmed and ornamental fish.
Pastuszka Anna   +3 more
doaj   +1 more source

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